NooCube review

How It Works For Brain Productivity?

By Nootropic Blend staff
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NooCube Review

NooCube for brain productivity is a popular dietary supplement to improve mental speed, motivation, and daily focus in healthy people. This natural nootropic stack uses 13 ingredients thoroughly studied when it comes to boosting cognitive function.

The manufacturer didn’t want to include caffeine, however, NooCube still resembles a “cup of Joe.” But, it gives a stim-free nootropic effect that lasts longer and there are no side effects like restlessness and shakiness usually attributed to this natural psychostimulant.

NooCube changed its look last year and updated the formulation with a few ingredients.

Our review explores whether the redesigned NooCube has been improved and will help you achieve better mental performance?


Table of Contents

NooCube manufacturer

NooCube is a UK product, manufactured by Glasgow-based Wolfson Brands company, that sells it worldwide. This manufacturer is credible in that it produces supplements in a GMP-certified FDA-certified facility from ingredients that are known as safe (GRAS). 

The products are scientifically-backed, use innovative technologies and strategies tested by top athletes and medical professionals.

Some brands you may be heard of are CrazyBulk, PhenQ, Bauer Nutrition, TestoPrime, XYZ Collagen, NiacinMax, and Garcinia Extra. 

NooCube is their only premium nootropic supplement.

As we said, Wolfson’s team of entrepreneurs, marketers, nutritionists, engineers, designers, and business explorers ensures that everything is compliant with FDA, GMP, and other regulations. This is one of the reasons why this safe synergistic blend competes really well with larger brands.

But let’s put marketing aside and examine how NooCube works. Is there enough quality to be called one of the best nootropics on the market?

NooCube Benefits

  • 13 ingredients

  • 60 capsules

  • 2 caps / day

  • 30 servings / month

  • $2.49 / serving

  • Best deal: Buy 3 get 3; 20% off first bottle with coupon 'SALE20'

NooCube review summary

  • NooCube is the advanced nootropic stack of vitamins, minerals, and herbal extracts.

  • NooCube uses 13 ingredients that have been well researched to improve the cognitive status, anecdotally and in human studies.

  • NooCube has a loyal following due to a lack of caffeine and other psychostimulants.

  • NooCube promises mental clarity for working professionals, students, and also for anyone getting a little older.

NooCube for brain productivity

Stim-free energy to boost brainpower; get 20% off using the coupon code "SALE20” 

Visit NooCube

NooCube testing for three months

One Noocube capsule on the top of bottle

Before I get into the details, it should be said how NooCube affected me in the period of three months.

NooCube usually works 30-60 minutes after taking it, if body tolerance is not interfering. Tolerance is a person’s reduced response to a drug or supplement, which occurs when used repeatedly and the body adjusts to its constant presence.

The recommended daily size is two capsules to start if you are using the supplement for the first time. But, you can safely take to four capsules, which is in my opinion a dose needed to notice NooCube’s full benefits.

The effects of NooCube last for approximately 4-6 hours.

I have noticed an increase in cognitive benefits during fitness training, verbal fluidity in social interactions, better working memory during long hours of work, healthier stress levels, and relaxation after work.

I would often feel a mental urge for productivity and find myself in a day filled with creativity. In some reviews, people compare this to a coach in your body who corrects your reactions to stress. This comparison stems from the merits of the adaptogen compounds that make up the NooCube.

So if you want to improve stress resistance and boost productivity in demanding scenarios, this supplement should work fine.

Read my 12-week NooCube case study.

Scientific evidence on the effectiveness of NooCube

The company cites 11 clinical studies of individual ingredients on the NooCube website.

Although these studies showed a positive effect of ingredients on cognitive functions, the doses included in the trials were higher than those used by the manufacturer in the formulation.

This is really important when evaluating the potency of this supplement.

We think that could mean a few things:

  • Some individual ingredients in NooCube will be somewhat weakened compared to those in the original research.

  • Nootropics act synergistically when ingredients are mixed, so their properties are enhanced even in smaller doses.

  • The results of NooCube stack will not be missed, but it will probably be different from individual to individual.

Thanks to which ingredients NooCube works?

NooCube primarily works because of the Bacopa Monnieri, which is included in a generous dose. It is close to that used in clinical trials. Since it takes 6-12 weeks of continuous use of this traditional memory booster to get it working, be patient before you start noticing all the benefits it offers.

Another powerful compound is Huperzine A that prevents the breakdown of acetylcholine levels, the main neurotransmitter for memory. This will improve the memory function even more overtime, which has already been emphasized by the use of Bacopa.

They also added Alpha GPC as a choline donor, which is involved in the production of this major neurotransmitter.

The use of the amino acids L-tyrosine and L-theanine is the reason why this supplement also works in the aspects of motivation, relaxed mood, and creativity.

Now, let’s find more about every ingredient.

NooCube ingredients


Choline donor – 50 mg


thumbnail of alpha amino acid structureBecause choline supplements are necessary to power your brain, which uses raw sources to produce acetylcholine, NooCube uses a popular nootropic Alpha GPC that does so. Alpha GPC is an efficient type of choline with effects subtle and intracellular, but it absorbs rapidly and supplies the brain. Alpha GPC contributes to the production of this vital neurotransmitter in sufficient amounts and works in synergy with other ingredients.

Huperzine A

Acetylcholine inhibitor – 100 mcg

close up of hupezia serrata or Huperzine-AHuperzine A is a naturally occurring compound purified from the plant called Huperzia Serrata. It is best known as the inhibitor of the acetylcholinesterase (AChE) enzyme that breaks down the ‘learning neurotransmitter’ acetylcholine. Huperzine A protects the brain by reducing free radicals and oxidative stress as well as plays a neuroprotective role by protecting brain cells from glutamate toxicity and increases nerve growth factor levels. 

Bacopa Monnieri (whole extract)

Adaptogen – 250 mg

close up of Bacopa Monnieri leafsSimilar to choline and Huperzine A, Bacopa Monnieri improves acetylcholine levels. Since Bacopa is a soothing agent, it brings levels of serotonin in balance and prevents anxiety and stress. These effects will be very notable in the NooCube supplement. Bacopa contains active substances bacosides involved in the transmission of nerve impulses to the brain stem. It boosts the growth of nerve endings called dendrites. Bacopa’s less known actions are that it inhibits inflammatory pathways in CNS. 

CAT'S CLAW concentrated EXTRACT 4:1

Adaptogen – 175 mg

close up of cat's claw (Unadegato) leafsCat’s Claw inner bark is in use in Peru and other South American countries by several native tribes over the centuries. Some traditional uses include antibacterial, antifungal, and immune system support. Science has long known the effective action of the plant ingredients on inflammatory processes and the stimulation of metabolism in deeper layers of skin, as well as the binding of free radicals in the body. Cat’s Claw is known for lowering blood pressure, too.


Adaptogen – 150 mg

close up of the oats strawAlthough enriching human nutrition with many wonderful qualities, Oat Straw is still used to feed cattle, especially horses, because it quickly restores power. Oat Straw provides a high level of energy and motivation for all-day activity and work. Oat straw increases the brain waves known as alpha-2 waves, which are emitted during active periods of the day when we are awake. This leads to better concentration, attention, mental processing, and the general state of alertness. Oat Straw prevents certain enzymes from breaking down dopamine. 


Amino acid – 100 mg

Close up fresh tea leaves in morning sunlightL-theanine is a calming compound associated with green tea. It’s great for promoting ”wakeful relaxation’ by boosting alpha brainwaves, only without stimulation or sedation. It also reduces stress levels and modulates natural “feel-good” neurotransmitters in the brain. Many people use it for creativity, productivity, and quiet focus. L-theanine is a real chill ingredient in NooCube. It is often paired with yet another amino acid called L-tyrosine for synergistic properties. They have very similar molecules but opposing effects. 


Amino acid – 250 mg

L Tyrosine

Unlike L-theanine that regulates neurotransmitters, L-tyrosine is producing them. It is a natural precursor to dopamine, epinephrine, and norepinephrine. This stimulatory amino acid reduces fatigue and stress, improves working memory, increases alertness and subjective well-being. Many scientific papers point to the main quality of L-tyrosine that it helps to improve mental performance in stressful conditions.


Antioxidant – 14,3 mg


Resveratrol is a free radical scavenger with a variety of beneficial effects on health. We relate its most important application to protecting blood vessels and the heart. It slows down blood clotting, lowers blood pressure, and prevents damage to blood vessels. Resveratrol also has a nootropic effect on the brain. It boosts BDNF, increases cerebral circulation, and improves energy and memory.


Antioxidant – 140 mcg


Pterostilbene, like its relative Resveratrol, maintains healthy cell function. It acts as a potent antioxidant and supports normal levels of blood sugar. Pterostilbene rejuvenates brain cells and supports motor function and cognitive abilities in adults suffering from memory changes.

Other ingredients include hydroxypropyl methylcellulose (for capsule formation), maltodextrin, dicalcium phosphate, silica, and magnesium stearate (as fillers, binders, and preservatives).

These inactive ingredients are not harmful, but it is better not to see them on the supplement’s labels.

What's new in NooCube formula?

NooCube dietary supplement

B vitamins

We need B vitamins as cofactors in the work of cognitive processes, and all good nootropic blends contain them. NooCube added three B vitamins to its formulation.

Vitamin B1 (Thiamine) maintains the health of the nerves and the heart. It is an essential cofactor for several enzymes involved in brain cell aerobic metabolism, cell growth, the transmission of nerve impulses, and acetylcholine synthesis. 

Vitamin B12 (as Cyanocobalamin) is important to maintain the health of your metabolism, blood cells, and nerves. Cyanocobalamin is a man-made form of vitamin B12 used to prevent and treat low blood levels of this vitamin. Unfortunately, NooCube doesn’t use methylcobalamin, which is a better form of B12.  

Biotin is an essential nutrient and water-soluble vitamin B group that acts as a coenzyme in the metabolism of proteins, fats, and carbohydrates. Biotin boosts the health of the hair and nails, too, and helps manage blood sugar levels, among other benefits. 

Lutein and zeaxanthin support

Lutemax 2020 is an award-winning addition from OmniActive Health Technologies. It is a source of lutein and zeaxanthin, carotenoids crucial not only for the eyes but also for the health of the brain and skin.

Lutemax 2020 is claimed to improve eye health and visual performance, reduce eye fatigue, and support sleep quality. Lutemax also supports cognitive function by being a pillar in eye strain, enabling focus and concentration.

In two studies, Lutemax shows to reduce levels of cortisol – a stress hormone – by almost 50 percent and significantly increase brain-derived neurotrophic factor (BDNF). This protein handles the survival of existing neurons and the growth and differentiation of new neurons and synapses.

NooCube side effects

Each person possesses unique biochemistry and does not respond to comparable conditions, drugs, or supplements in the same way.

As I mentioned, in more sensitive individuals, tolerance will develop over time, perhaps after three to four weeks of continuous use of the NooCube.

So keep in mind that it is good to take a break from using it two days a week. 

NooCube capsules are safe, and it’s unlikely you’ll respond with headaches, diarrhea, nausea, or vomiting which are some rare symptoms associated with natural nootropics.

But there is a possibility that some people who take too many capsules may experience side effects.

To prevent side effects, use a source of good fats because some ingredients absorb better that way.

Omega-3 or coconut oil like this MCT oil goes great with any nootropic stack.

One last caution is the presence of Huperzine A in the formulation.

Due to the long half-life of Huperzine A, biohackers often recommend cycling off to not build a tolerance to this drug.  

Also, in NooCube’s disclaimer, they require you to consult a physician if you are already taking medications or long history of allergy.

Where to buy NooCube?

The official NooCube website is the best place to order the supplement with discounts and special promotions. They are quite generous once you are a loyal customer.

Other NooCube retailers cannot afford such promotions.

NooCube offers a little too generic customer support for my taste, but delivery is free regardless of the quantities ordered. Also, their return policy is great, so there is no risk when purchasing.

Their website also encourages people to shop in bundles to significantly reduce costs of single ingredients.

‘Buy 3, Get 3 free’ deal is a pretty decent value exchange for a six-month period of use.

The list of various multi-buy package options:

  • single bottle: $59.99 $74.99| TOTAL SAVINGS: $15.00

  • double pack (2 bottles + 1 FREE): $119.99 $224.97| TOTAL SAVINGS: $104.98

  • triple pack (3 bottles + 3 FREE): $179.99 $449.94| TOTAL SAVINGS: $269.95

If for any reason you are not satisfied, simply return the unused bottles to the original container within 67 days of receiving the order. NooCube will give you a 100% refund–excluding shipping charges.

NooCube vs Alpha Brain

NooCube formula is reminiscent of Alpha Brain, one of the first commercial nootropic stacks. Upon closer inspection, we noticed a great similarity between the two stacks. Therefore, NooCube is built on an already well-known and successful combination of ingredients.

While Alpha Brain increased the doses of its ingredients, NooCube remained completely transparent in detecting the doses of each ingredient. That’s a plus on its part. Also, NooCube has a better price for this kind of formulation.

NooCube vs Mind Lab Pro

That is the death race in terms of the popularity of ingredients put in their stacks. Obviously, both companies have great marketing and know-how to promote all-natural products.

While both stacks have a similar feel, Mind Lab Pro is a little different because it’s made from the best form of ingredients. They put in all the best extracts and made a great effort in the right ingredients. And putting it together with professionalism and details that became the industry gold standard.

The consequence is that MLP will not cause tolerance after some time.

While NooCube remains a cheaper supplement good for starters, the Mind Lab Pro seems deeper and more influential for the long-term benefits. So go for it if you have the extra money to invest.

Pros and Cons



NooCube brain productivity review

NooCube for brain productivity

Stim-free energy to boost brainpower; get 20% off using the coupon code "SALE20” 

Visit NooCube


With a new look and rethought formulation, NooCube for brain productivity is a solid dietary supplement for cognitive support.

The ingredients are backed up with a lot of clinical studies, so they are safe for individuals of all ages. Because of ingredients that improve visual performance, it’s now probably even better suited for the middle-aged and +55 folks. 

Their refund policy is safe, and the shipping is free worldwide.

Here are some additional suggestions for users to get the maximum from using NooCube.

  • Add Omega-3 or MCT oil supplements to get better absorption of ingredients

  • Replicate NooCube blend with stronger single ingredients and learn to stack nootropics

  • Upgrade Noocube with racetams if you want a stronger boost

  • Buy the same ingredients and try them as single nootropics

If you are looking for more recommendations for pre-made nootropic stacks, then check our next article.

Nootropics that boosts your brain power

Read about 6 best pre-made nootropic stacks you should check

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