NooCube Review 2023 | A New Formula For More Brain Benefits?

NooCube review - three bottles on the table


NooCube is a highly regarded dietary supplement that is designed to boost brain performance and improve memory recall and focus. It contains a blend of natural extracts, vitamins, and amino acids that work together to enhance mental clarity, memory function, and focus. The supplement is suitable for a wide range of individuals, including students, working professionals, and anyone seeking to improve their cognitive abilities. If you’re looking for a solution to boost your brain power, NooCube might be the answer you’re searching for.

Overall Rating: 4

Table of Contents

NooCube Review summary

Overall rating:
Medical Benefits
  • 13 ingredients

  • 60 capsules

  • 2 caps / day

  • 30 servings / month

  • $ 2 / serving

  • Best deal: Buy 3 get 3; 20% off first bottle with coupon 'SALE20'


  • NooCube is a blend of 13 natural ingredients including vitamins, minerals, amino acids, and herbal extracts
  • These ingredients have been scientifically proven to have positive effects on the brain
  • NooCube does not contain caffeine or other psychostimulants, making it safe for people of all ages
  • The blend of ingredients is designed to deliver optimal results for improved mental clarity
  • Ideal for professionals, students, and individuals over 55 who want to maintain their mental sharpness

NooCube brain productivity

Stim-free supplement to boost brainpower; get 20% off

use the coupon code "SALE20” 

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What is NooCube?

NooCube is a nootropic supplement made with 13 natural ingredients that have been researched for their cognitive benefits. Unlike other products, NooCube does not contain caffeine and instead uses a blend of natural ingredients to boost brain function without any stimulant side effects.

NooCube can be taken alongside a cup of coffee, helping to neutralize the negative effects of caffeine while still providing a mental boost. The supplement has recently been upgraded, and this review explores the effectiveness of the new formula. Additionally, alternatives to NooCube are also discussed.

NooCube's manufacturer

NooCube is a dietary supplement manufactured by Wolfson Brands, a company based in Glasgow, UK, and sold globally. The company’s team of experts, including entrepreneurs, nutritionists, engineers, designers, and business professionals, ensures that NooCube meets regulations such as FDA and GMP.

One reason for NooCube’s success is its safe, GRAS ingredients that compete with larger brands. The product is backed by science and has been tested by top athletes and licensed healthcare professionals using innovative technologies and strategies.

NooCube is among several well-known brands such as CrazyBulk, PhenQ, Bauer Nutrition, TestoPrime, XYZ Collagen, NiacinMax, and Garcinia Extra.

Putting aside the marketing aspect, let’s focus on how NooCube works. Is it of high enough quality to be considered one of the best nootropics on the market?

How to take NooCube?

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I would like to share my personal journey with NooCube, a dietary supplement that promises to enhance brain productivity and promote better memory recall and daily focus. Over the course of three months, I put NooCube to the test and was pleasantly surprised by the results.

Within just 15 to 45 minutes of taking NooCube, I noticed a significant increase in mental clarity and focus. These effects lasted for an impressive 4+ hours, giving me the mental edge I needed to tackle my daily tasks. The recommended daily dose is two capsules, but I found that taking up to four capsules provided even greater benefits. However, it’s important to take occasional breaks to prevent tolerance, which can occur when the body adjusts to the constant presence of the supplement.

Every person’s experience with NooCube may vary, but for me, the results were clear and tangible. I noticed a significant improvement in my cognitive function during fitness training, enhanced verbal fluidity in social interactions, better working memory in the office, reduced brain fog, improved stress management, and increased relaxation and wellness after work.

In short, NooCube was like having a personal coach in my body, helping me to handle stress and achieve my goals. If you’re looking to improve your cognitive abilities, boost productivity, and increase resilience in demanding situations, NooCube may be the answer you’ve been searching for.

One Noocube capsule on the top of bottle
90 Days of testing NooCube

Scientific evidence

The NooCube website cites 11 clinical studies of the individual ingredients that make up the supplement. While these studies showed promising results for cognitive function improvement, it is important to note that the doses used in the trials were higher than those included in the NooCube formula.

This difference could mean a few things:

  • The potency of some individual ingredients in NooCube may be somewhat weakened compared to the original research.
  • However, the nootropics in NooCube work in synergy to enhance each other’s properties, even in smaller doses.
  • The effects of NooCube may vary from person to person.

What Makes NooCube Work? NooCube is primarily powered by Bacopa Monnieri, a memory booster that is included in a generous dose, similar to that used in clinical trials. It may take up to 6-12 weeks of consistent use to fully experience its benefits.

Another key component is Huperzine A, which helps maintain acetylcholine levels, the neurotransmitter responsible for memory. This, combined with Bacopa Monnieri, boosts memory function even more over time.

Alpha GPC is also added as a choline donor, which is involved in the production of the acetylcholine neurotransmitter.

L-tyrosine and L-theanine, the amino acids in NooCube, contribute to the supplement’s effects on motivation, mood, and creativity.

Let’s take a closer look at each ingredient and its role in the supplement.

NooCube ingredients

NooCube label
NooCube label


Choline donor – 50 mg

thumbnail of alpha amino acid structure

Because choline supplements are necessary to power your brain to produce acetylcholine, NooCube uses a popular nootropic Alpha GPC that does so. Alpha GPC is an efficient type of choline with effects subtle and intracellular, but it absorbs rapidly and supplies the brain. Alpha GPC contributes to the production of this vital neurotransmitter in sufficient amounts and works in synergy with other compounds. Read more

Huperzine A

Acetylcholine inhibitor – 100 mcg

close up of hupezia serrata or Huperzine-A

Huperzine A is a naturally occurring compound purified from the Huperzia Serrata plant. It is best known as the inhibitor of the acetylcholinesterase (AChE) enzyme that breaks down the ‘learning neurotransmitter’ acetylcholine. Huperzine A protects the brain by reducing free radicals and oxidative stress and plays a neuroprotective role by protecting brain cells from glutamate toxicity and increasing nerve growth factor levels. Read more

Bacopa Monnieri (whole extract)

Adaptogen – 250 mg

close up of Bacopa Monnieri leafs

Similar to choline and Huperzine A, Bacopa Monnieri improves acetylcholine levels. Since Bacopa is a soothing agent, it brings serotonin to balance and prevents anxiety and stress. These effects will be very notable in the NooCube supplement. Bacopa contains active substances bacosides, involved in the transmission of nerve impulses to the brain stem. It boosts the growth of nerve endings called dendrites. Bacopa’s less known actions are that it inhibits inflammatory pathways in CNS. Read more

CAT'S CLAW concentrated EXTRACT 4:1

Adaptogen – 175 mg

close up of cat's claw (Unadegato) leafs

Cat’s Claw inner bark comes from Peru and other South American countries. Several native tribes used it over the centuries. Some traditional uses include antibacterial, antifungal, and immune system support. Science has long known the effective action of the plant ingredients on inflammatory processes and stimulation of metabolism in deeper layers of skin, as well as the binding of free radicals in the body. Cat’s Claw is known for lowering blood pressure, too. Read more


Adaptogen – 150 mg

close up of the oats straw

Although enriching human nutrition with many qualities, Oat Straw is still used to feed cattle, especially horses, because it quickly restores power. Oat Straw provides high energy levels and motivation for all-day activity. Oat straw increases the brain waves known as alpha-2 waves, emitted during active periods of the day when we are awake. That leads to better concentration, attention, mental processing, and a general state of alertness. Oat Straw prevents certain enzymes from breaking down dopamine. Read more


Amino acid – 100 mg

Close up fresh tea leaves in morning sunlight

L-theanine is a calming compound associated with green tea. It promotes relaxation by boosting alpha brainwaves, only without stimulation or sedation. It also reduces stress levels and modulates natural “feel-good” neurotransmitters flow to the brain. Many people use it for creativity, productivity, and enhanced focus. L-theanine is a chill ingredient in NooCube. It is in pair with another amino acid called L-tyrosine for synergistic properties. They have very similar molecules but opposing effects. Read more


Amino acid – 250 mg

L Tyrosine

While L-theanine regulates neurotransmitters, L-tyrosine produces them. It is a natural precursor to dopamine, epinephrine, and norepinephrine. This stimulatory amino acid reduces fatigue and stress, improves working memory, and increases alertness and subjective well-being. Many scientific papers point to the quality of L-tyrosine that it helps to improve mental performance in stressful conditions. Read more


Antioxidant – 14,3 mg


Resveratrol is a free radical scavenger with beneficial effects on health. We relate its most important application to protecting blood vessels and the heart. It slows down blood clotting, lowers blood pressure, and prevents damage to blood vessels. Resveratrol also has a nootropic effect on the brain. It boosts BDNF, increases cerebral circulation, and improves energy and memory.


Antioxidant – 140 mcg


Pterostilbene, like its relative Resveratrol, maintains healthy cell function. It acts as a potent antioxidant and supports normal levels of blood sugar. Pterostilbene rejuvenates brain cells and supports motor function and cognitive abilities in adults suffering from memory changes.

Other ingredients: This supplement also contains additional ingredients such as hydroxypropyl methylcellulose (for capsule formation), maltodextrin, dicalcium phosphate, silica, and magnesium stearate, which serve as fillers, binders, and preservatives.

While these components are considered safe, it is generally preferable to not find them listed on a supplement label.

What's new in NooCube formula?

Three bottles of NooCube and two capsules
NooCube label

B vitamins are essential for cognitive processes and all quality nootropics contain them. NooCube includes three B vitamins in its formulation.

Thiamine, also known as Vitamin B1, helps maintain the health of the heart and nerves and is a necessary cofactor for various enzymes involved in the brain’s aerobic metabolism, cell growth, nerve impulse transmission, and acetylcholine synthesis.

Vitamin B12, in the form of Cyanocobalamin, supports the health of the metabolism, blood cells, and nerves, but it would have been more beneficial if NooCube used methylcobalamin instead.

Biotin, a water-soluble B-group vitamin, acts as a coenzyme in protein, fat, and carbohydrate metabolism and offers additional benefits such as promoting hair and nail health and regulating blood sugar levels.

Lutemax 2020, a product from OmniActive Health Technologies, is an award-winning ingredient in NooCube’s formula. It is a source of lutein and zeaxanthin, carotenoids that are important not only for eye health but also for brain and skin health. Studies have shown that lutein and zeaxanthin intake can improve information processing speed, reasoning ability, memory, visual motor reaction, attention, verbal and visual performance, and cognitive flexibility.

Lutemax 2020 also promotes eye health, reduces eye fatigue, and supports sleep quality, and its benefits for cognitive function are reflected in its ability to reduce eye strain and enhance focus and concentration. In two studies, Lutemax decreased cortisol levels by almost 50% and significantly increased brain-derived neurotrophic factor (BDNF), a protein responsible for the survival of existing neurons and the growth of new neurons and synapses.

NooCube side effects

Individual biochemistry is unique, so the response to comparable conditions, drugs, and supplements can vary. Medical conditions, health, body metabolism, and medications can also impact how supplements affect you.

Continuous use of NooCube for three to four weeks may lead to tolerance in sensitive individuals, so it’s suggested to take a break for two days a week. NooCube is generally considered safe, but excessive consumption may lead to rare side effects such as headaches, diarrhea, nausea, or vomiting.

To prevent side effects, consume good fats like this MCT oil, and consider cycling the supplement. Huperzine A, an ingredient in NooCube, has a long half-life and cycling is often recommended to avoid tolerance. If you are taking medications or have a history of allergies, it’s advised to consult a doctor.

Where to buy NooCube?

The official NooCube website is the best place to purchase the product with discounts and promotions. As a loyal customer, you can expect generous offers. Other retailers may not be able to provide the same promotions. Although NooCube’s customer support may not be personalized, they offer cost-free delivery and a safe return policy. The website also suggests purchasing in bulk to reduce costs.

Multi-buy options include:

  • Single bottle: Original price $74.99, now $59.99 with a savings of $15.00
  • Double pack (2 bottles plus 1 free): Original price $224.97, now $119.99 with a savings of $104.98
  • Triple pack (3 bottles plus 3 free): Original price $449.94, now $179.99 with a savings of $269.95

You can return unused bottles within 67 days of receiving your order for a 100% refund, excluding shipping charges.

NooCube comparison

NooCube Modafinil Smart Caffeine Optimind


NooCube brain productivity review

Modafinil pill

best choice

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best choice

Heightened focus

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Increased alertness

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Reduced fatigue

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Faster learning capacity

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Reduced anxiety

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Health safety

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Price tag

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NooCube vs Smart caffeine

“Smart Caffeine” by Natural Stacks is a combination of caffeine and L-theanine, which offer short-term benefits such as increased mental energy and improved concentration and alertness. Although it can be stacked with other nootropics, it does not provide significant results on its own.

NooCube, on the other hand, is a blend of various types of nootropics that enhance focus, memory, and mental speed. It has the potential to provide greater benefits compared to Smart Caffeine and promises to improve cholinergic transmission, which has a positive impact on learning and memory enhancement.

NooCube vs Alpha Brain

The NooCube formula is similar to that of Alpha Brain, one of the original commercial nootropic stacks. On closer examination, the similarities between the two are apparent. As a result, NooCube began with a solid foundation. Both supplements are quite comparable.

While Alpha Brain has increased the dose and potency of its ingredients, NooCube has taken a safer approach by being transparent about its dosages. This is a positive aspect of NooCube and it also offers a more affordable price for its formula compared to Alpha Brain.

Noocube vs Optimind

Optimind by AlternaScript employs caffeine and Sulbutiamine to enhance focus and energy levels. However, the exact dosages of the ingredients are undisclosed, making it difficult to predict its long-term effects.

While it provides a boost in energy and short-term cognitive benefits, it may lead to long-term instability and a rapid tolerance buildup.

In contrast, NooCube offers gentle natural stimulation without caffeine, providing a sustained mental boost.

Noocube vs Modafinil

Modafinil is a prescription drug primarily used to treat sleep-related disorders and as a fast-acting brain stimulant for 12+ hours of enhanced productivity and a range of cognitive benefits. It also assists individuals with ADHD in improving their concentration and focus. However, heavy usage of Modafinil can lead to dependence and disrupt the brain’s chemical balance.

In comparison, NooCube is a safe option for long-term use and provides solid benefits.

NooCube alternatives

Mind Lab Pro is a prime example of professionalism and attention to detail in the industry, setting the gold standard. The brand is supported by an ongoing official clinical trial, making it an exceptional choice. In terms of long-term benefits, Mind Lab Pro is cleaner and more effective than most other products available.

For entrepreneurs, students, night-shift workers, and startups, Modalert by ModafinilXL, a generic version of Provigil, is another option to consider. This company offers free modafinil samples, allowing you to test the effects of generic Provigil on your body without any additional cost.

Mind-Lab-Pro label of ingredients

Mind Lab Pro

  • Scientifically proven by independent research. Rated No.1 for focus, clarity, memory, mood, long-range brain health.

  • Mind Lab Pro is one of the cleanest brain supplements ever established.

  • No pointless additives and unnecessary ingredients – just pure, high-potency nootropic nutrients.

  • Side effects are very rare. Some people have headaches, stomach cramps, or nausea. If you find this brand makes you sleepy, you may want to consider buying the ingredients separately and introducing them one by one over a period of weeks to months.

  • Less affordable if you're eating on a tight budget

  • Can only buy direct from manufacturer

Modafinil pill


  • Modalert by ModafinilXL is a prescription-free premium generic version of Provigil — the world’s first safe “smart drug.”

  • It is approved as safe by the Food and Drug Administration for treating excessive daytime dullness and sleepiness caused by 3 sleep disorders.

  • Many healthy individuals who buy this drug do so for its cognitive enhancing benefits.

  • Just like any other medication, there are side effects with the use of Modalert.

  • Side effects are often experienced by some first-time users. It has lower potential for addiction, when compared with several other “smart drugs,” or nootropics.

  • Modalert interacts with alcohol, caffeine, some foods, and certain other medications.

NooCube pros & Cons



Quality score:

NooCube brain productivity review

NooCube brain productivity

Stim-free supplement to boost brainpower; get 20% off

use the coupon code "SALE20” 

Visit NooCube

NooCube review conclusion

NooCube is a dietary supplement made from natural ingredients that support cognitive function. It is based on ingredients backed by human clinical trials, though more long-term research on nootropics is needed.

The supplement is well received by customers, although some may have concerns about the dosage. NooCube is safe for people of all ages and is not a scam. The new formula provides improved visual performance and enhanced mental and cognitive health, making it particularly suitable for middle-aged and older adults. Wolfson Brands offers a secure refund policy and free worldwide shipping.

To maximize the benefits of NooCube, consider adding Omega-3 or MCT oil supplements, stacking it with other nootropics, upgrading with racetams, or trying the individual ingredients as single nootropics. If you’re looking for more pre-made nootropic stack recommendations, stay tuned for our next article.

Nootropics that boosts your brain power

Read about 6 best pre-made nootropic stacks you should check

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