NooCube Review 2023 | A New Formula For More Brain Benefits?

NooCube review - three bottles on the table


NooCube for brain productivity is a popular dietary supplement to improve memory recall and daily focus. This blend of herbal extracts, vitamins, and amino acids is good to try if looking to improve your mental clarity, memory recall and focus.

Overall Rating: 4

Table of Contents

NooCube Review summary

Overall rating:
Medical Benefits
  • 13 ingredients

  • 60 capsules

  • 2 caps / day

  • 30 servings / month

  • $ 2 / serving

  • Best deal: Buy 3 get 3; 20% off first bottle with coupon 'SALE20'


  • NooCube is the synergistic nootropic blend of vitamins, minerals, amino acids, and herbal extracts

  • 13 natural ingredients have been researched over the years to prove cognitive effects

  • The ingredients forms are satisfying enough to bring the results

  • Lack of caffeine and other psychostimulants

  • NooCube promises mental clarity for professionals, students, and +55 who want to keep their intellectual capacity.

NooCube brain productivity

Stim-free supplement to boost brainpower; get 20% off

use the coupon code "SALE20” 

Visit NooCube

What is NooCube?

NooCube contains 13 natural ingredients studied to have nootropic effects. It’s also a caffeine-free supplement that energizes the brain by giving you a stim-free vibe.

Some say that NooCube goes perfectly with a cup of joe. You can really enjoy a cup of excess at the start of the day as this supplement will neutralize the side effects of caffeine. The real office supplement, you might say.

The NooCube team has upgraded the formulation with several ingredients, and this review explores how good is this new formula. You may also read about NooCubes alternatives.

NooCube's manufacturer

NooCube is manufactured in the UK by Glasgow-based Wolfson Brands company and sells worldwide. Their team of entrepreneurs, marketers, nutritionists, engineers, designers, and business explorers ensures that everything is compliant with FDA, GMP, and other regulations.

That is one of the reasons why this synergistic blend, made from safe ingredients (GRAS), competes well with large brands.

Their products are backed by science and use innovative technologies and strategies tested by top athletes and licensed healthcare professionals.

Some brands you may have heard of are CrazyBulk, PhenQ, Bauer Nutrition, TestoPrime, XYZ Collagen, NiacinMax, and Garcinia Extra. 

But let’s put marketing aside and examine how NooCube works. Is it quality enough to be called one of the best nootropics on the market?

How to take NooCube?

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Before I get into the details, I should say how NooCube affected me over three months.

When I first tried this blend, I found it works 15-45 minutes after taking it. The effects of NooCube last for solid 4+ hours. 

The recommended daily size is two capsules to start if you are using the supplement for the first time. But, you can safely take up to four capsules to notice full benefits.

You will need to take occasional breaks to be sure the body tolerance is not interfering. Tolerance is a person’s reduced response to a drug or supplement, which occurs when used repeatedly and the body adjusts to its constant presence.

The experience will be different between groups of users.

My takeaways from taking NooCube:

  • increased cognitive benefits during fitness training
  • verbal fluidity in social interactions
  • improvement of working memory during hours in the office
  • less brain fog
  • healthier stress levels and better mood
  • wellness time after work.

I have often felt mental clarity without the annoying brain fog and remember days filled with creativity.

In some reviews, people compare NooCube with a coach in your body. The one to correct your reactions to stress. This comparison stems from the values of the adaptogen ingredients in the stack.

If you want to improve stress resistance and boost productivity in demanding scenarios, NooCube should work well.

One Noocube capsule on the top of bottle
90 Days of testing NooCube

Scientific evidence

The company cites 11 clinical studies of individual ingredients on the NooCube website.

Although these studies showed a positive effect on cognitive functions, the doses included in the trials were higher than those used by the manufacturer in the formulation.

That is important when evaluating the potency of this supplement.

We think that could mean a few things:

  • Some individual ingredients in NooCube will be somewhat weakened compared to those in the original research.

  • Nootropics act in synergy when blending natural ingredients, so their properties are enhanced even in smaller doses.

  • The results won’t be missed but might differ from individual to individual.

Picture of 2 bottles of NooCube with A-Z multivitam bottle from Bauer Nutrition
NooCube with Bauer Nutrition A-Z multi

Thanks to what ingredients does NooCube work?

NooCube primarily works because of the Bacopa Monnieri, included in a generous dose. It is close to that used in clinical trials. Since it takes 6-12 weeks of continuous use of this traditional memory booster to get it working, be patient before you start noticing all the benefits it offers.

Another powerful compound is Huperzine A which prevents the breakdown of acetylcholine levels, the neurotransmitter for memory. That will improve the memory function even more over time, which has already been emphasized by using Bacopa.

They’ve also added Alpha GPC as a choline donor, involved in the acetylcholine neurotransmitter production.

The amino acids L-tyrosine and L-theanine are the reason why this supplement also works on motivation, relaxed mood, and creativity.

Now, let’s find out more about every ingredient.

NooCube ingredients

NooCube label


Choline donor – 50 mg

thumbnail of alpha amino acid structure

Because choline supplements are necessary to power your brain to produce acetylcholine, NooCube uses a popular nootropic Alpha GPC that does so. Alpha GPC is an efficient type of choline with effects subtle and intracellular, but it absorbs rapidly and supplies the brain. Alpha GPC contributes to the production of this vital neurotransmitter in sufficient amounts and works in synergy with other compounds. Read more

Huperzine A

Acetylcholine inhibitor – 100 mcg

close up of hupezia serrata or Huperzine-A

Huperzine A is a naturally occurring compound purified from the Huperzia Serrata plant. It is best known as the inhibitor of the acetylcholinesterase (AChE) enzyme that breaks down the ‘learning neurotransmitter’ acetylcholine. Huperzine A protects the brain by reducing free radicals and oxidative stress and plays a neuroprotective role by protecting brain cells from glutamate toxicity and increasing nerve growth factor levels. Read more

Bacopa Monnieri (whole extract)

Adaptogen – 250 mg

close up of Bacopa Monnieri leafs

Similar to choline and Huperzine A, Bacopa Monnieri improves acetylcholine levels. Since Bacopa is a soothing agent, it brings serotonin to balance and prevents anxiety and stress. These effects will be very notable in the NooCube supplement. Bacopa contains active substances bacosides, involved in the transmission of nerve impulses to the brain stem. It boosts the growth of nerve endings called dendrites. Bacopa’s less known actions are that it inhibits inflammatory pathways in CNS. Read more

CAT'S CLAW concentrated EXTRACT 4:1

Adaptogen – 175 mg

close up of cat's claw (Unadegato) leafs

Cat’s Claw inner bark comes from Peru and other South American countries. Several native tribes used it over the centuries. Some traditional uses include antibacterial, antifungal, and immune system support. Science has long known the effective action of the plant ingredients on inflammatory processes and stimulation of metabolism in deeper layers of skin, as well as the binding of free radicals in the body. Cat’s Claw is known for lowering blood pressure, too. Read more


Adaptogen – 150 mg

close up of the oats straw

Although enriching human nutrition with many qualities, Oat Straw is still used to feed cattle, especially horses, because it quickly restores power. Oat Straw provides high energy levels and motivation for all-day activity. Oat straw increases the brain waves known as alpha-2 waves, emitted during active periods of the day when we are awake. That leads to better concentration, attention, mental processing, and a general state of alertness. Oat Straw prevents certain enzymes from breaking down dopamine. Read more


Amino acid – 100 mg

Close up fresh tea leaves in morning sunlight

L-theanine is a calming compound associated with green tea. It promotes relaxation by boosting alpha brainwaves, only without stimulation or sedation. It also reduces stress levels and modulates natural “feel-good” neurotransmitters flow to the brain. Many people use it for creativity, productivity, and enhanced focus. L-theanine is a chill ingredient in NooCube. It is in pair with another amino acid called L-tyrosine for synergistic properties. They have very similar molecules but opposing effects. Read more


Amino acid – 250 mg

While L-theanine regulates neurotransmitters, L-tyrosine produces them. It is a natural precursor to dopamine, epinephrine, and norepinephrine. This stimulatory amino acid reduces fatigue and stress, improves working memory, and increases alertness and subjective well-being. Many scientific papers point to the quality of L-tyrosine that it helps to improve mental performance in stressful conditions. Read more


Antioxidant – 14,3 mg


Resveratrol is a free radical scavenger with beneficial effects on health. We relate its most important application to protecting blood vessels and the heart. It slows down blood clotting, lowers blood pressure, and prevents damage to blood vessels. Resveratrol also has a nootropic effect on the brain. It boosts BDNF, increases cerebral circulation, and improves energy and memory.


Antioxidant – 140 mcg


Pterostilbene, like its relative Resveratrol, maintains healthy cell function. It acts as a potent antioxidant and supports normal levels of blood sugar. Pterostilbene rejuvenates brain cells and supports motor function and cognitive abilities in adults suffering from memory changes.

Other ingredients include hydroxypropyl methylcellulose (for capsule formation), maltodextrin, dicalcium phosphate, silica, and magnesium stearate (fillers, binders, and preservatives).

These inactive ingredients are not harmful, but it is better not to see them on the supplement’s labels.

What's new in NooCube formula?

Three bottles of NooCube and two capsules
NooCube label

B vitamins

We need B vitamins as cofactors in the work of cognitive processes, and all good nootropic blends contain them. NooCube added three B vitamins to its formulation.

  • Vitamin B1 (Thiamine) maintains the health of the nerves and the heart. It is an essential cofactor for several enzymes involved in brain cell aerobic metabolism, cell growth, the transmission of nerve impulses, and acetylcholine synthesis. 
  • Vitamin B12 (as Cyanocobalamin) maintains the health of your metabolism, blood cells, and nerves. Cyanocobalamin is a synthetic form of vitamin B12 used to prevent and treat low blood levels of this vitamin. Unfortunately, NooCube doesn’t use methylcobalamin, a better format for vitamin B12.  
  • Biotin is an essential nutrient and water-soluble vitamin B group that acts as a coenzyme in the metabolism of proteins, fats, and carbohydrates. Biotin boosts the health of the hair and nails, too, and helps manage blood sugar levels, among other benefits. 

Lutein and zeaxanthin improve mental performance

Lutemax 2020 is an award-winning addition from OmniActive Health Technologies. It is a source of lutein and zeaxanthin, the carotenoids crucial not only for the eyes but also for the brain and skin health.

Human studies show that intake of lutein and zeaxanthin can increase:

  • Speed of information processing (1, 2) 
  • Reasoning ability (3
  • Memory (4, 5)
  • Visual motor reaction (6
  • Attention (7, 8
  • Verbal and visual performance (9, 10
  • Cognitive flexibility is the ability to shift mental strategies according to the task (11

Lutemax 2020 improves eye health and visual performance, reduces eye fatigue, and supports sleep quality. Lutemax also supports cognitive function by being a pillar in eye strain, enabling focus and concentration.

In two studies, Lutemax reduces levels of cortisol – a stress hormone – by almost 50 percent and significantly increases brain-derived neurotrophic factor (BDNF). This protein handles the survival of existing neurons and the growth and differentiation of new neurons and synapses.

NooCube side effects

Each person possesses unique biochemistry and does not respond the same to comparable conditions, drugs, or supplements. Remember that certain medical conditions, your health, your body metabolism, and any medications could affect how you feel supplements.

As I mentioned, in more sensitive individuals, tolerance will develop over time, perhaps after three to four weeks of continuous use of the NooCube.

So keep in mind to take a break from using it two days a week. 

Capsules of NooCube are safe, and it’s unlikely you’ll respond with headaches, diarrhea, nausea, or vomiting, rare symptoms associated with natural nootropics.

But there is a possibility that some people who take too many capsules may experience side effects.

To prevent side effects, use a source of good fats because some ingredients absorb better that way.

Omega-3 or coconut oil like this MCT oil goes with any nootropic stack.

One last caution is the presence of Huperzine A in the formulation.

Due to the long half-life of Huperzine A, biohackers often recommend cycling it to avoid tolerance.  

Also, in NooCube’s disclaimer, they require you to consult a physician if you are already taking medications or have a long history of allergies.

Where to buy NooCube?

The official website is the best place to order NooCube with discounts and special promotions. They are generous once you are a loyal customer.

Other NooCube retailers cannot afford such promotions.

NooCube offers a little too generic customer support for my taste, but delivery is cost-free regardless of the quantities ordered. Also, their return policy is safe, so there is no risk when purchasing.

Their website also encourages people to shop in bundles to reduce the costs of single ingredients.

Buy 3, Get 3 free, and get 60% off is a decent value exchange for six months of use.

The list of various multi-buy package options:

  • single bottle: $59.99 $74.99| TOTAL SAVINGS: $15.00

  • double pack (2 bottles + 1 FREE): $119.99 $224.97| TOTAL SAVINGS: $104.98

  • triple pack (3 bottles + 3 FREE): $179.99 $449.94| TOTAL SAVINGS: $269.95

You can return the unused bottles to the original container within 67 days of receiving the order. NooCube will give you a 100% refund–excluding shipping charges.

NooCube comparison

NooCube Modafinil Smart Caffeine Optimind


NooCube brain productivity review

Modafinil pill

best choice

best choice

best choice

Heightened focus

Increased alertness

Reduced fatigue

Faster learning capacity

Reduced anxiety

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three stars graphic

Health safety

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Price tag

four dollar coins

NooCube vs Smart caffeine

Smart caffeine by Natural Stacks is a nootropic stack consisting of caffeine and L-theanine. The two ingredients can give you desirable short-term effects like boosting mental energy and helping you to concentrate and be more alert. It’s suitable for stacking with other nootropics, but alone it doesn’t do anything huge.

NooCube is a “synergistic” blend of several nootropic types that help enhance and support focus, memory, and mental speed. NooCube has the potential to do a lot more than Smart Caffeine alone and promises better cholinergic transmission that affects learning and memory enhancement. 

NooCube vs Alpha Brain

NooCube formula is reminiscent of Alpha Brain, one of the first commercial nootropic stacks. Upon closer inspection, we noticed a similarity between the two stacks. Therefore, NooCube started on a well-known ground. Both are very much alike supplements.

While Alpha Brain has increased the doses and effects of its ingredients, NooCube has remained transparent and on the safer side of dosage. That’s a plus on its part. Also, NooCube has a better price for this kind of formulation.

Noocube vs Optimind

Optimind by AlternaScript uses caffeine and Sulbutiamine to promote attention and increase energy levels. Unfortunately, the doses of the ingredients are unknown, and the Optimind feels vague and hard to predict long-term.

While it is a solid supplement for energy and short-term cognitive effects, it causes long-term instability and the likelihood of a rapid tolerance build-up.

NooCube, on the other hand, has mild natural stim effects with zero caffeine and has a sustainable mental boost.

Noocube vs Modafinil

The primary effect of the prescription drug Modafinil is to help individuals who suffer from sleep-related disorders and healthy people who want a fast-acting brain stimulator for 12+ hours of productivity and a myriad of cognitive benefits.

It also helps people diagnosed with attention-deficit hyperactivity disorder (ADHD) to improve concentration and focus. Many individuals take it heavily. That can cause dependence and ruin your brain’s chemical balance.

On the other hand, NooCube is safe to bet for long-term use. And the benefits are solid.

NooCube alternatives

Mind Lab Pro has put together professionalism and details that became the industry gold standard. They also have an ongoing official clinical trial of their brand, which is splendid. Mind Lab Pro is cleaner and better for the long-term benefits than most products on the market.

Another prescription-free solution that comes to mind, especially for entrepreneurs, startups, students, and night-shift workers, is a generic version of Provigil, the Modalert made by ModafinilXL. This company suggests you test the impact of generic Provigil on your body at no extra cost, with free modafinil samples.

Mind-Lab-Pro label of ingredients

Mind Lab Pro

  • Scientifically proven by independent research. Rated No.1 for focus, clarity, memory, mood, long-range brain health.

  • Mind Lab Pro is one of the cleanest brain supplements ever established.

  • No pointless additives and unnecessary ingredients – just pure, high-potency nootropic nutrients.

  • Side effects are very rare. Some people have headaches, stomach cramps, or nausea. If you find this brand makes you sleepy, you may want to consider buying the ingredients separately and introducing them one by one over a period of weeks to months.

  • Less affordable if you're eating on a tight budget

  • Can only buy direct from manufacturer

Modafinil pill


  • Modalert by ModafinilXL is a prescription-free premium generic version of Provigil — the world’s first safe “smart drug.”

  • It is approved as safe by the Food and Drug Administration for treating excessive daytime dullness and sleepiness caused by 3 sleep disorders.

  • Many healthy individuals who buy this drug do so for its cognitive enhancing benefits.

  • Just like any other medication, there are side effects with the use of Modalert.

  • Side effects are often experienced by some first-time users. It has lower potential for addiction, when compared with several other “smart drugs,” or nootropics.

  • Modalert interacts with alcohol, caffeine, some foods, and certain other medications.

NooCube pros & Cons



Quality score:

NooCube brain productivity review

NooCube brain productivity

Stim-free supplement to boost brainpower; get 20% off

use the coupon code "SALE20” 

Visit NooCube

NooCube review conclusion

NooCube for Brain Productivity is a dietary supplement made from proven natural ingredients that we recommend using for cognitive support.

Individual ingredients are backed up with human clinical trials, although a shortage of long-term studies still exists about nootropics.

Customers’ reviews of NooCube are generally positive. The customers like it, while others sometimes complain about the dosage of the stack.

NooCube remains safe for individuals of all ages, and it is not a scam.

The new formula improves visual performance and adds up to mental and cognitive health. Now, this supplement is even more suitable for middle-aged and over-55s.

Wolfson Brands offers a secure refund policy, and shipping is free worldwide.

Here are some additional suggestions for users to get the maximum from using NooCube.

  • Add Omega-3 or MCT oil supplements to get better absorption of ingredients

  • Replicate the NooCube blend with better single ingredients and learn to stack nootropics

  • Upgrade Noocube with racetams nootropics if you want a more powerful boost

  • Buy the same natural ingredients and try them as single nootropics

How well does all this sound to you?

If you are looking for more recommendations for pre-made nootropic stacks, then check our next article.

Nootropics that boosts your brain power

Read about 6 best pre-made nootropic stacks you should check

Best nootropic stacks