The 6 Best Nootropic Stacks To Enhance Performance

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Many people prefer trying single ingredients before delving into DIY stacking nootropics. However, for those looking for simplicity and efficiency, ready-made nootropic stacks in capsules are a convenient option. These premade stacks save time, minimize side effects, and can be cost-effective for neurohackers.

Some reasons to use it include:

  • If you are a beginner and want to try how complex combinations work

  • If you don’t want all that weird gadgetry – part of the DIY process

  • If you want to take efficient nootropics when you are at a go

We reviewed the 6 best nootropics stacks.

Table of Contents

Best premade nootropic stacks

6 best nootropic stacks
Brands Manufacturers Rating

Wolfson Berg Limited

Natural Stacks

Opti-Nutra LTD

Nootripure Laboratories

Neurohacker Collective

Opti-Nutra LTD

NooCube nootropic stack for mental speed and reduced stress

Picture of NooCube bottles for best nootropic stack review

“There are over 124,000 smarter people in the world today thanks to NooCube.”

– NooCube

NooCube has gained significant popularity in its initial years, reflecting the growing demand for natural nootropics and the surge in interest in “smart drugs.” A team of neuroscientists responded to this trend by creating a blend of well-researched, medically-backed natural ingredients. NooCube enhances focus, mental speed, and memory, noticeably boosting overall brain function and body efficiency.

NooCube is designed to be safe and not overly stimulating. It lacks caffeine and other energy fillers, relying on natural mental power, making it suitable for beginners in nootropic use. The manufacturer has backed the product with transparency, multiple research studies, substantial research, and years of scientific trials on its ingredients.

label of the ingredients in the 'NooCube' formulation
NooCube list of ingredients

What makes NooCube special?

NooCube is a nootropic supplement that boosts memory and cognition by enhancing neurotransmitter production, particularly acetylcholine. It speeds up mental processes, supports neuron growth, strengthens brain synapses, and provides antioxidant benefits.

Key ingredients include Bacopa Monnieri, Huperzine-A, Alpha GPC, L-theanine, L-tyrosine, Out straw, and Cat’s Claw.

Benefits include improved memory, reduced stress, enhanced concentration, mood boost, creativity support, and increased libido. NooCube is suitable for various age groups and professions, including students and professionals. It’s non-addictive and can have lasting memory benefits even after discontinuation.

Suggested dosage: 2 capsules with meals or fatty acids. You can go up to 4 capsules daily.

Read in-depth NooCube review



NEUROFUEL (CILTEP) nootropic stack for memory and focus

Picture of NEUROFUEL bottle and caps for best nootropic stack review

Better brain better life. Use NEUROFUEL to remain sharply motivated and focused for hours.”

– Natural Stacks

NEUROFUEL, formerly known as CILTEP, is a nootropic stack that has remained impressive for nearly a decade since its accidental discovery on the Longecity forum. Distributed by Natural Stacks, known as the world’s first open-source supplement company, it prides itself on transparency.

Despite its apparent simplicity, this 100% natural stack offers competitive advantages. It enhances concentration, focus, and memory, both in the short and long term.

CILTEP stands for “chemically-induced long-term potentiation,” a biological process that underlies the brain’s ability to form and retain new knowledge and memories. While the concept behind CILTEP (NEUROFUEL) is theoretical and anecdotal, it has garnered attention and positive feedback from users worldwide due to its effective results.

CILTEP list of ingredients

What makes NEUROFUEL special?

NEUROFUEL, also known as CILTEP, is a unique nootropic blend that combines three distinct pharmacological classes of chemicals to stimulate synaptic plasticity.

The theory behind CILTEP is that artichoke extract, a source of luteolin, acts as a PDE4 inhibitor, raising cAMP levels. Forskolin further boosts cAMP levels by inhibiting its degradation, creating a significant elevation in cAMP levels and facilitating Long Term Potentiation (LTP) mediated by CREB.

Benefits of NEUROFUEL:

  1. Enhances focus and combats brain fog.
  2. Boosts key neurotransmitters like acetylcholine, dopamine, and epinephrine.
  3. Increases cognitive capacity and mental speed.
  4. Enhances motivation.
  5. Optimizes mental energy.
  6. Improves concentration.
  7. Supports long-term memory recall.
  8. Stabilizes mood and social skills.

NEUROFUEL users include students, scientists, doctors, business executives, filmmakers, and various professionals seeking improved mental focus and cognitive performance in their daily lives.

Recommended dosage: Take 1-3 capsules per day in the morning on an empty stomach.

Read in-depth CILTEP review



Performance Lab Mind nootropic stack for stim-free energy and brain health

Picture of Performance Lab Mind bottles for best nootropic stack review

“The only nootropic that enhances cognition and helps your brain recover from intense mental exertion

– Performance Lab

Performance Lab is a UK-based supplements company, known for its rigorous testing and certifications. Their products are manufactured in the USA and cover various aspects of health, including sleep, vision, cognition, energy, and exercise.

Performance Lab Mind is a nootropic designed to enhance cognition and combat stress burnout while supporting overall brain health. It contains four key ingredients that work synergistically:

  1. Cognizin® (Citicoline): Boosts brain energy, supports brain cell function, and enhances learning, attention, and memory.

  2. Sharp-PS® Green (Phosphatidylserine): Promotes Nerve Growth Factor (NGF), aids in brain regeneration, neurogenesis, and neural repair, and optimizes brain cell membranes.

  3. Maritime Pine Bark Extract (95% proanthocyanidins): Provides antioxidants that combat free radicals, enhance brain plasticity, and relax blood vessels for improved nutrient delivery to the brain.

  4. Ajipure® L-Tyrosine: Supports the synthesis of brain chemicals like epinephrine, norepinephrine, and dopamine, helping to combat stress and improve focus.

This nootropic stack works on multiple brain pathways simultaneously, offering noticeable benefits over time. However, results may take some time to become evident.

List of 'Performance Lab Pro' ingredients label
Performance Lab Mind label

What makes Performance Lab Mind special?

Performance Lab Mind (PLM) is a unique nootropic stack that includes a prebiotic-infused NutriCaps® capsule for better absorption. It’s known for its compatibility with other Performance Lab products and has received praise for its high-quality ingredient blend and value.

PLM offers caffeine-free, stim-free mental energy, improved focus, faster reactions, enhanced memory, reduced brain fog, improved mood, and hormone balance. It’s suitable for professionals in high-pressure situations, the elderly, and anyone looking for peak mental performance.

Suggested dosage: Opti Nutra recommends taking 1-2 capsules of Performance Lab Mind in the morning or early afternoon.



THRIIV nootropic stack for mental clarity, enhanced recall, reduced stress, and productivity

Picture of THRIIV package for best nootropic stack review

“The most effective cognitive enhancement product in the world.

– Nootripure Laboratories

THRIIV by Nootripure Laboratories is a newcomer in the nootropic market, gaining attention for its quick-acting 12-hour energy boost formula. It’s designed to enhance creativity, confidence, and concentration for maximum productivity, and it has shown promise during beta testing.

This stack is developed by a team of scientists and medical experts with diverse backgrounds, including Ayurvedic and Chinese medicine. THRIIV combines herbs, extracts, neuro-vitamins, and other nootropic compounds for a comprehensive cognitive enhancement solution.

Nootripure is committed to providing premium supplements and offers an educational program to help users achieve their health goals. They aim to deliver the most effective cognitive enhancement in the world and have customized their product line to cover various nootropic targets.

THRIIV stands out as a nootropic stack for energy, focus, and peak cognitive performance, offering a mix of natural and synthetic compounds for enhanced productivity while maintaining safety.

THRIIV list of ingredients

What makes THRIIV special?

THRIIV contains Nootriplex, in-house developed cannabinoid formula that enhances cognitive functions and uplifts mood.

NewCaff™, an innovative caffeine product that offers steady absorption without disrupting the body’s balance.

THRIIV contains 15 top-quality ingredients, including adaptogens, neuroprotective agents, and cannabinoids, promoting relaxation, focus, and anti-anxiety effects. It offers a potent nootropic effect, improving productivity, mental clarity, confidence, memory, and creativity, making it suitable for students, professionals, and athletes.

Suggested dosage: take 2 capsules a day with a meal. To avoid desensitization of effect THRIIV should be cycled.

Read in-depth THRIIV review



Qualia Mind nootropic stack for enhanced focus, memory, and mental clarity

Picture of Qualia Mind bottle for best nootropic stack review

Imagine more. Dream bigger. Go make it happen.

– Neurohacker Collective

Qualia Mind is a nootropic supplement specifically designed to enhance focus, energy, mental clarity, working memory, and mood regulation. It stands out as a superior option compared to other brands in the nootropic market.

What sets Qualia Mind apart is the involvement of a management team at Neurohacker Collective known for their innovative thinking. The product is the result of collaboration between diverse thinkers, scientists, and doctors, including those from Stanford University.

Qualia Mind goes beyond conventional brain supplements and is aimed at aiding the future of humankind. Its reputation as one of the most potent nootropic stacks is well-established, as it addresses multiple cognitive goals and delivers both immediate and lasting benefits.

list of the ingredients in the Qualia Mind supplement
Qualia Mind list of ingredients

What makes Qualia Mind special?

Qualia Mind is an advanced nootropic stack with 28 vegan-friendly ingredients, including neuro-vitamins, adaptogen extracts, amino acids, choline donors, and antioxidants. It’s well-known for its potent formulation and careful selection of high-quality ingredients.

Benefits of Qualia Mind include enhanced mental clarity, the ability to enter a flow state, increased energy, productivity, focus, and reduced procrastination. Users also report mood enhancement, greater creativity, and improved linguistic and mental sharpness.

This supplement delivers effects in about 40 minutes, providing calm, focused energy throughout the day without excessive stimulation. It’s suitable for various users, including professionals and fitness enthusiasts.

Suggested dosage: Up to 7 capsules per day. The optimal dosage of Qualia may vary based on your chemistry. Start with the 5 capsules. To avoid desensitization of effect, Qualia Mind should be cycled. We recommend taking 2 days off each week.

Read in-depth Qualia Mind review



Mind Lab Pro® nootropic stack for cognitive improvements in all aspects

Picture of Mind Lab Pro bottle and caps for best nootropic stack review

100% brain power. 

– Opti-nutra LTD

Mind Lab Pro® is a highly recommended nootropic stack known for its comprehensive approach to optimizing memory, mental performance, mood, stress resistance, maintenance, and brain repair. It’s developed by Opti Nutra Advanced Nutraceutical, the same company behind Performance Lab Pro®.

With eleven ingredients, Mind Lab Pro® is an advanced version of Performance Lab Mind and is considered a classic example of an effective pre-made stack. It stands out for its all-natural composition, including plant-based capsules and eco-friendly packaging.

Mind Lab Pro® aims to unlock the full potential of every aspect of your brain, making it a golden industry standard for pre-made nootropic stacks. Despite the emergence of newer stacks, it continues to be a top choice in the industry.

Mind Lab Pro list of ingredients

What makes Mind Lab Pro special?

Mind Lab Pro® stands out for its full-spectrum nootropic ingredients, ensuring users receive a wide range of benefits. Some notable extracts in Mind Lab Pro® include Citicoline (Cognizin®), Phosphatidylserine (Sharp PS® Green), Bacopa Monnieri, Lion’s Mane Mushroom, and Maritime Pine Bark Extract. These ingredients target various brain pathways, promoting brain energy, neurotransmitters, cerebral circulation, neuroprotection, and more.

The benefits of Mind Lab Pro® include:

  • Improved short- and long-term memory
  • Enhanced alertness, concentration, focus, and motivation
  • Faster and better decision-making
  • Reduced anxiety levels
  • Improved mood and quality of life

Mind Lab Pro® is considered one of the best nootropic stacks available, offering well-studied and pure compounds with minimal risk of adverse effects. It is suitable for students, athletes, professionals, competitors, and the elderly seeking cognitive support.

Suggested dosage: two capsules with meals last the entire day.

Read in-depth Mind Lab Pro review



What nootropic stacks to look for?

Nootropic stacking can be done through two methods:

  1. Self-formulated nootropic stack: This DIY approach allows experienced users to experiment with individual nootropics, dosages, and components to create customized stacks.

  2. Pre-made nootropic stack: Companies offer pre-formulated stacks suitable for beginners and the elderly. These convenient options provide proven stack benefits and reduce the risk of side effects compared to mixing your own components. Some vendors offer custom pre-made stacks for specific cognitive goals.

Effective cognitive enhancement doesn’t rely solely on targeting a single chemical reaction or adding a single ingredient for energy. Instead, it involves a coordinated approach that takes into account multiple pathways and factors.

Manufacturers of quality pre-made nootropic stacks invest in optimizing their formulations to:

  1. Improve Absorption: Enhance the absorption of bioactive compounds to ensure they reach their intended targets in the body and brain.

  2. Increase Potency: Amplify the potency of ingredients to achieve stronger and more consistent cognitive benefits.

  3. Amplify Benefits: Create synergy among ingredients to enhance overall cognitive benefits, such as memory, focus, and mood regulation.

  4. Reduce Side Effects: Minimize the risk of adverse effects by carefully selecting and balancing the ingredients in the stack.

By addressing these factors, pre-made nootropic stacks can provide users with a more comprehensive and effective cognitive enhancement experience. It’s important for consumers to choose stacks from reputable companies that prioritize these optimization strategies.

Creating targeted nootropic stacks for specific cognitive goals, along with recommending suitable ingredients for motivation, studying, anxiety, ADHD, and focus, is crucial for helping individuals achieve their desired cognitive outcomes.

Focusing on factors like increasing synergy, improving absorption, and mitigating side effects in pre-made nootropic stacks emphasizes the importance of creating effective and well-rounded cognitive enhancement solutions.

It’s essential for users to consider these aspects when selecting the right pre-made nootropic stack that aligns with their cognitive enhancement objectives.

How to choose nootropic stack?

When searching for the best pre-made nootropic stack, consider the following factors:

  1. Efficacy: Determine whether the supplement effectively improves cognitive performance, but keep in mind that individual responses may vary.

  2. Quality of Preparation: Assess how well the stack is formulated, considering ingredient sources, dosages, and transparency.

  3. Alignment with Goals: Ensure that the stack aligns with your specific cognitive goals to avoid unnecessary components.

Additional guidance includes:

  1. Avoid Proprietary Blends: Be cautious of products with proprietary blends that hide ingredient dosages. Transparent labeling is preferred.

  2. Bioavailable Ingredient Forms: Look for stacks that use standardized natural extracts for optimal bioavailability and potency.

  3. Correct Dosing: Verify that the dosage is neither too low to be effective nor excessively high, potentially causing side effects.

  4. No Fillers or Additives: Check the list of “other ingredients” for additives, preservatives, fillers, or synthetic compounds that could lead to unwanted side effects.

  5. Sample Usage: Consider trying a sample of the stack if available, as it allows you to assess the product before committing to a full purchase.

  6. Medical Advice: Consulting a medical specialist, undergoing blood tests, and qEEG brain mapping can help identify specific neurological deficiencies and guide your nootropic choices.

Picture of the man in front of the board looking for best nootropic stacks
How to find the best nootropic stack?

Conclusion: Is there a best nootropic stack?

The question of whether there is a single “best” nootropic stack is technically NO. The effectiveness of a nootropic stack depends on an individual’s specific goals, biology, and brain chemistry. People are biochemically unique, and what works for one person may not work the same way for another. Nootropic stacks should be chosen based on personal needs, body weight, and sensitivity to optimize their benefits. Therefore, the best nootropic stack is the one that works for your specific goals and unique physiology.

When considering a pre-made nootropic stack, factors like formulation strategy, ingredient quality, transparency, benefits, side effects, user experiences, reviews, budget, and value should all be taken into account.

Ultimately, the best nootropic stack for someone is a highly individualized choice. Each of the pre-made blends we mentioned here can be effective brain tools for exploring the potential of nootropics, but the winner will vary from person to person based on their unique circumstances and preferences. It’s important for you to do your research and perhaps even try all of these great stacks to determine what works best for you.

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