- Nootropic Blend staff
- Updated June 15, 2024
- Affiliate disclosure
We prioritize readers, not ads. Editorial independence. Free, factual information. A small fee from product links, no extra cost to you.
In our perpetual quest for optimal health and longevity, selecting a top-quality NMN (Nicotinamide Mononucleotide) supplement is crucial. NMN has gained significant attention for its potential to support cellular health and combat age-related decline. As a precursor to the vital NAD+ coenzyme, NMN plays a pivotal role in various metabolic processes, DNA repair, and cellular energy production.
With numerous brands vying for attention in the NMN supplement market, it’s essential to separate the wheat from the chaff. The brands we’ll explore today stand out for their unwavering commitment to purity, potency, and quality control, ensuring you receive the best possible tools to support your well-being.
Let’s delve into the world of NMN supplements and discover the leading names in the industry, backed by scientific research, third-party testing, and customer testimonials.
Table of Contents
Understanding NMN and Choosing a Supplier
Selecting the right NMN supplement hinges on several critical factors, including:
- Purity and Potency: The supplement’s purity and potency levels can significantly impact its effectiveness and safety profile.
- Source and Formulation: The source of the NMN, as well as any additional ingredients in the formulation, can influence bioavailability and potential interactions.
- Third-Party Testing: Reputable brands will subject their products to rigorous third-party testing to verify purity, potency, and safety, providing transparency through accessible lab reports.
- Bioavailability: The supplement’s delivery method (e.g., oral capsules, liposomal, sublingual) can affect how efficiently the body absorbs and utilizes the NMN.
- Customer Reviews and Reputation: Trusted brands will have a solid reputation backed by positive customer reviews, attesting to the quality and efficacy of their products.
With these factors in mind, let’s explore the top NMN supplement brands for 2025.
Best NMN supplement brands in 2025
| Product | Brand | Ingredients / Dosage per serving | Serving / Price |
|---|---|---|---|
|
|
|
ß – Nicotinamide Mononucleotide 900 mg Ergothioneine 4 mg Trans-Resveratrol 100 mg Vitamin D3 20 mcg |
Serving size: 2 Vegetarian capsules Servings per container: 30 Cost per serving: $2.93 |
|
|
|
ß – Nicotinamide Mononucleotide (NMN) 250 mg Nicotinamide Adenine Dinucleotide (NAD+) 190 mg Nicotinamide Riboside (NR) 160 mg Niacin 125 mg |
Serving size: 2 Vegetarian capsules Servings per container: 45 Cost per serving: $1.88 |
|
|
|
ß – Nicotinamide Mononucleotide (NMN) 250 mg (From 500 mg liposomal NMN) |
Serving size: 1 Vegetarian capsules Servings per container: 60 Cost per serving: $1.07 |
|
|
  |
Longevir™ NMN (β-Nicotinamide mononucleotide) 250 mg |
Serving size: 2 HPCM vegan capsules Servings per container: 30 Cost per serving: €2 |
|
|
|
β-nicotinamide mononucleotide (NMN) 1000 mg |
Serving size: 2 capsules Capsules in bottle: 366 Cost per serving: €2.57 |
|
|
|
β-nicotinamide mononucleotide (NMN) 1000 mg |
Serving size: 2 capsules Servings per container: 30 Cost per serving: $3.83 |
|
|
|
β-Nicotinamide mononucleotide (NMN)* with >99% certified purity 15 gram = 1x 15 g pouch |
Daily serving size: e.g., 1 g Net Weight: 30 g Price per Serving: 1.80 € |
NMN Supplement brand #1 - Wonderfeel
Wonderfeel Youngr NMN has certainly made waves in the health and wellness scene, and after diving into the details, it’s clear to see why. With a robust formula that combines a hefty dose of NMN with other beneficial ingredients, it’s positioned as a top contender in the anti-aging supplement market.
One of the standout features of Wonderfeel Youngr NMN is its comprehensive approach to health and wellness. With an innovative blend of 900 mg NMN with other high-powered antioxidants and longevity power players like resveratrol, ergo, hydroxytyrosol, and vitamin D3, Wonderfeel offers both the exciting benefits of taking an NMN supplement and the benefits of several other organic compounds.
Not only does it aim to boost energy levels and improve sleep quality, but it also supports skin health, enhances organ function, and even aids cognitive improvement. Because of its multifaceted approach to wellness and incorporation of several powerful ingredients, Wonderfeel Youngr is appealing to those seeking holistic well-being.
For those seeking the most affordable NMN supplement on the market with an optimal dosage of NMN and other supportive vitamins and ingredients, Wonderfeel Youngr™ is the best supplement to choose. Their subscription option makes the price a no-brainer, and the high quality of the formula, developed by Dr. Andrew Salzman, is singular. For those looking to approach wellness with a dynamic and multi-pronged approach, this vitamin-packed formula is the best way to go.
Backed by a team of experts and manufactured in FDA-certified facilities, Wonderfeel Youngr NMN prioritizes quality and safety. The absence of known adverse effects, supported by research and expert opinion, further reinforces its credibility as a reliable supplement choice.
What customers say about Wonderfeel
Customer feedback for Wonderfeel NMN highlights its numerous benefits, including increased energy levels, improved sleep quality, and positive changes in skin appearance. Users across different age groups have reported enhanced endurance and performance, particularly during workouts, along with feeling refreshed and rejuvenated upon waking. The absence of negative side effects emphasizes the product’s safety and quality, reinforcing Wonderfeel NMN as a trusted option for supporting overall health and vitality.
Pros
- Patented Formula Including Beneficial Antioxidants and Vitamins
- Robust, Optimal Dosage
- Increased Energy Levels
- Improved Sleep Quality
- Positive Effects on Skin
- Trusted Choice, and High Standards of Manufacturing
- Convenient Subscription Plan
Cons
- No Money-Back Guarantee
NMN Supplement brand #2 - Renue By Science
NAD⁺ Complete by Renue By Science is a groundbreaking supplement designed to support overall health and longevity. This comprehensive 4-in-1 supplement combines NAD⁺, NMN, NR, and niacin, simplifying your daily supplement routine. What sets NAD⁺ Complete apart is its utilization of cutting-edge liposomal delivery technology.
This innovative method significantly enhances the absorption of these vital compounds, providing up to six times better bioavailability compared to traditional supplements. Moreover, the liposomal delivery system reduces the risk of potential liver-related issues, allowing for the safe consumption of more effective dosages.
Individual responses to supplements can vary, influenced by factors such as age, overall health, and lifestyle. While both NAD+ and NMN are essential for cellular energy production, some users have reported distinct experiences with NAD⁺ Complete. Users have found relief from joint pain and improved sleep quality while using the liposomal versions of these supplements. This enhanced bioavailability may contribute to these positive effects.
Switching to liposomal NMN and NAD+ formulations, like those offered by Renue By Science, has been reported to result in sustained energy throughout the day and potentially more regular circadian rhythms. The traditional powder forms of these compounds, while effective, tend to provide a more immediate “boost” of energy. This shift to a smoother, more subtle energy boost can be a desirable outcome for individuals seeking sustained vitality. Additionally, some users have taken NAD level tests and reported improved NAD levels after using liposomal supplements.
Ultimately, the choice between traditional powder and liposomal supplements may depend on individual preferences and desired outcomes. The convenience, absorption efficiency, and reported benefits of liposomal NMN and NAD+ supplements, such as those from Renue By Science, make them an attractive option for individuals looking to support their overall well-being and vitality.
What customers say about Renue By Science
Users on Reddit largely express trust in Renue by Science as a supplier of NMN supplements, citing its legitimacy and quality. Some users mention that Renue has been mentioned by well-known figures such as Andrew Huberman. However, there are a few comments suggesting that customer service and communication could be improved, and the pricing of their products has been a point of discussion, especially for international customers.
Pros
- Offers NMN in wide variety of forms and formulations
- Third-party tested for purity and safety (over 99% purity)
- Manufactured in an FDA-approved facility with cGMP certification
- Vegan-friendly, with no artificial additives
- Maximizes nutrient absorption for optimal results
Cons
- No return policy for opened/used products
NMN Supplement brand #3 - Hello100
Hello100 excels in the realm of longevity supplements with its specialized focus on liposomal NMN and Resveratrol products. These supplements are designed to maximize bioavailability, ensuring that the active ingredients are effectively absorbed by the body for optimal results.
Manufactured in cGMP-certified facilities in the USA, Hello100 products undergo rigorous testing to guarantee purity and safety. This commitment to quality assurance is particularly reassuring for consumers seeking reliable and effective supplements to support healthy aging processes.
With a recent upgrade to their NMN and Resveratrol offerings, Hello100 continues to emphasize sustainability and efficacy in promoting long-term health benefits. Their products are priced competitively, making them accessible to individuals looking for affordable solutions without compromising on quality.
By focusing on transparency and offering a 60-day money-back guarantee, Hello100 reinforces its commitment to customer satisfaction and trust. Whether you’re exploring NMN and Resveratrol for the first time or seeking to enhance your current regimen, Hello100 provides a dependable choice for supporting overall health and vitality through aging.
What customers say about Hello100
Hello NMN receives a range of feedback from users, with many praising its benefits. Customers report increased energy, improved well-being, stronger nails, and better sleep.
The company’s responsiveness is also appreciated. The quick, informative responses and improved energy and mood from the product, make it a sustainable option.
However, some users find the benefits subtle or slow. They note incremental stamina and energy boosts but still await better sleep improvements. Some users saw no changes after 30 days and plan to reassess after 90 days.
Criticisms focus on dosage and delivery. Some users feel the dosage is too low for older or heavier individuals, while delivery delays frustrate some users. Despite these issues, Hello NMN’s proactive responses show a commitment to customer satisfaction.
Pros
- High Purity and cGMP-certified quality
- NMN free of other ingredients, at a competitive price.
- Liposomal Delivery maximizes nutrient absorption for optimal results
- Offers a generous 60-day money-back guarantee and free shipping within the US
Cons
- Lower dosage per capsule
NMN Supplement brand #4 - Purovitalis
Purovitalis is a European-based company renowned for its high-purity NMN supplements, boasting an impressive 99% purity. These supplements are manufactured in GMP-certified facilities, ensuring quality and safety. Purovitalis uses liposomal technology to enhance the bioavailability of their NMN capsules, with each serving containing 250 mg of NMN. The recommended daily dosage is two capsules.
Purovitalis offers a range of options, including 30, 60, or 120 capsule quantities. They also provide pure NMN powder in bottles ranging from 15 to 120 grams. For those seeking a combination of NMN and resveratrol, Purovitalis offers a bundle designed for a 2-month supply. They provide worldwide shipping at reasonable rates, with $6.99 standard shipping available in the USA, and an express delivery option for $14.99.
Customers who have used Purovitalis NMN supplements have reported increased energy, better sleep, enhanced skin health, and quicker recovery after workouts. Purovitalis prioritizes purity, transparency, and safety, conducting third-party testing to maintain the highest quality.
Their NMN is sourced from a reputable European manufacturer, and their products are produced in cGMP-certified facilities. They offer various capsule quantities and a subscription option for savings, all backed by a 30-day money-back guarantee.
In summary, Purovitalis is a top choice for individuals seeking pure and effective NMN supplements to support their longevity and overall health journey.
What customers say about Purovitalis
Customers on Trustpilot have praised Purovitalis for efficient delivery, positive product experiences, and good customer service, with some noting noticeable energy and health benefits from the products.
Pros
- Impressive 99% purity, reflecting their commitment to quality
- High absorption rate
- No unwanted additives – it's pure NMN through and through
- UV Protection Glass Containers
Cons
- Slightly Higher Price Tag
- Lower Dosage per Capsule
NMN Supplement #5 - DoNotAge
DoNotAge (DNA), a UK-based company that offers a pure β-Nicotinamide Mononucleotide (β-NMN) supplement with a remarkable 99% purity, containing 1000 mg (1 g) of NMN per serving. This is delivered in the form of two non-liposomal capsules. DoNotAge stands out by providing the highest amount of NMN per serving compared to other products on the market, making it a potent choice. Their product is vegan-friendly and free from artificial ingredients, allergens, and preservatives.
DoNotAge’s NMN capsules contain 500mg of non-liposomal NMN and are manufactured by Uthever, a well-known NMN producer from China. While the capsules are slightly larger due to the high NMN content, they may pose a challenge for some individuals to swallow. Each package includes 60 capsules, equivalent to a one-month supply, and is well-sealed to maintain product quality.
Quality and safety are paramount to DoNotAge, as the product undergoes regular third-party testing, and is manufactured in a GMP-certified facility. The ISO9001 standards are also adhered to during production.
DoNotAge’s NMN supplement is available exclusively on its official website, and it is not sold on Amazon in the US. While the price is somewhat above average compared to other NMN providers, DoNotAge’s commitment to providing high-quality NMN with transparency and testing ensures their product’s reliability and effectiveness.
What customers say about DoNotAge
The Trustpilot reviews of DoNotAge, a health supplement company, reflect a range of opinions. Many customers express satisfaction with the product quality, prompt delivery, and customer service. They report positive health effects, from improved skin to reduced inflammation. Some praise the company’s concise product selection and transparency. However, a few negative reviews mention concerns about misleading advertising, suggesting that the company may need to improve its transparency and communication.
Pros
- High NMN purity and potency
- Good manufacturing standards
- Vegan-Friendly
- Non-Liposomal option for those with specific preferences
Cons
- Slightly above average in terms of cost
- The capsules are larger than regular ones
NMN Supplement #6 - ProHealth Longevity
ProHealth Longevity offers a range of NMN (Nicotinamide Mononucleotide) supplements designed to promote overall well-being and potentially support anti-aging efforts. These supplements feature high-quality NMN as the primary ingredient, with a focus on enhancing NAD+ (Nicotinamide Adenine Dinucleotide) levels in the body.
ProHealth Longevity’s NMN products come in various forms, such as capsules, powders, tablets, and lozenges, providing flexibility in how users choose to incorporate NMN into their daily routines. These supplements are known for their pharmaceutical-grade quality and purity, having undergone third-party testing to ensure potency and absence of heavy metals.
Users of ProHealth Longevity NMN supplements have reported benefits like increased energy levels, improved cognitive function, and potential anti-aging effects. The formulations also include additional beneficial components like vitamin D, Bioperine, Ergothioneine, and Hydroxytyrosol.
For individuals looking to elevate their NAD+ levels and potentially experience improvements in cellular function, cognitive performance, and overall vitality, ProHealth Longevity NMN products offer a trusted and comprehensive range of options. Additionally, ProHealth Longevity provides discounts, money-back guarantees, and free shipping, making these supplements accessible to those seeking to support their health and well-being.
What customers say about ProHealth
Customers’ reviews on Judge.me for ProHealth’s NMN products are largely positive. Many users report increased energy, improved focus, and positive effects on their workouts. Some users mention enhanced endurance and stamina, making it suitable for physical activities. Users appreciate the convenience of the products, and they find them effective in countering age-related issues. While these reviews are generally favorable, it’s important to keep in mind that individual experiences may vary, and results may depend on factors like age, lifestyle, and overall health.
Pros
- Offers NMN in various forms
- Pharmaceutical-Grade Quality
- Additional Beneficial Ingredients
- Responsive Customer Service
- The supplements are reasonably priced
Cons
- Individual Variability
- Potential Side Effects
NMN Supplement #7 - Moleqlar
Uthever® NMN by MoleQlar shines as a prime choice for those seeking top-quality NMN products. Their exceptional purity level of over 99% is a testament to their commitment to delivering the best. The fact that it’s part of a significant clinical trial further demonstrates its effectiveness. Notably, it remains stable even under rigorous conditions, assuring customers of its unwavering quality.
While there’s a mention on their website of NMN not being intended for human consumption under German and European law, the availability of this product for personal use is a win for those looking to explore its potential benefits.
While price points might be somewhat higher compared to other powdered options, it’s important to remember that quality often comes with a cost. When you prioritize product excellence, this could be a justifiable investment.
In summary, Uthever® NMN sets a high standard in the world of NMN supplements, and MoleQlar provides a valuable gateway for individuals to access this premium product. It’s reassuring to see such quality options available for those looking to support their health and well-being.
What customers say about MoleQlar
Customers on Reviews.io have given mostly positive feedback about MoleQlar’s products and services. They appreciate the quality of the products and prompt delivery. Some customers noted that it was too early to comment on product effectiveness. While a few expressed concerns about the price and one customer mentioned a delivery delay, MoleQlar responded to this issue, explaining the shipping timeline. Overall, customers seem satisfied with MoleQlar’s offerings and customer service.
Pros
- Full-Spectrum Near-Infrared Light
- Part of a major NMN clinical trial
- Rigorously tested for quality
- Multiple product variants available
Cons
- No measuring spoon included in the delivery
- Slightly higher prices compared to other options
- Legal Considerations
FAQ NMN and NAD+
1. What Is NMN (Nicotinamide Mononucleotide)?
NMN is a compound that serves as a precursor to nicotinamide adenine dinucleotide (NAD+), a critical molecule for cellular function. It is produced through the conversion of nicotinamide and ribose-containing nucleosides.
2. What Is NAD+?
Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme essential for cellular functions, including glycolysis, fatty acid metabolism, and the Krebs cycle. NAD+ plays a crucial role in redox reactions within cells.
3. How Is NAD+ Made?
NAD+ can be synthesized through various pathways, including de novo synthesis, Preiss-Handler pathway, and the salvage pathway. The salvage pathway, involving NMN conversion to NAD+, is a rapid and efficient method.
4. How Do NMN Supplements Raise NAD+ Levels?
NMN supplements increase NAD+ levels by acting as a precursor for NAD+ in the salvage pathway. This pathway is more efficient in NAD+ production compared to de novo synthesis. NMN is orally bioavailable and quickly absorbed into the bloodstream.
5. What Are the Cellular Health Benefits of NAD+?
NAD+ is crucial for various biochemical reactions, including glycolysis, fatty acid storage, and ATP production. It plays a role in maintaining cellular health and energy levels in the mitochondria and cytoplasm.
6. What Is the Difference Between NR and NMN Supplements?
Nicotinamide riboside (NR) is another precursor to NAD+ through the salvage pathway. NR requires additional steps to convert to NAD+, while NMN is one step away from NAD+. NMN supplements are more readily converted into NAD+.
7. Are NMN Supplements Safe?
Both animal and human studies have shown that NMN supplements are safe. In animal studies, adverse effects were minimal at lower doses, and clinical trials in humans demonstrated increased NAD+ levels without adverse effects on vital signs.
8. How Does NMN Supplementation Affect Cellular Function?
NMN supplementation enhances cellular respiration, allowing for the efficient conversion of macronutrients to ATP. This leads to increased energy production and improved cellular function, particularly in skeletal muscle.
9. How Does NMN Affect Longevity and Aging?
Aging is associated with decreased NAD+ levels, leading to age-related diseases. NMN supplements can increase NAD+ levels, potentially reversing age-associated gene expression and promoting healthy aging.
10. How Does NMN Affect Cerebral Blood Flow and Cognition?
NMN increases NAD+ levels, which promote neurovascular coupling and improve cerebral blood flow. This can lead to enhanced cognitive function, improved memory, and coordination.
11. How Does NMN Affect Cardiovascular Health?
NMN supplementation can reverse the NADH/NAD+ ratio imbalance, leading to improved heart health. It maintains pro-survival capabilities of cardiac cells and supports cardiac activity.
12. Can NMN Supplements Help with Neurological Disorders?
NMN supplements may benefit individuals with neurological disorders such as Alzheimer’s and Parkinson’s disease by improving mitochondrial function and reducing oxidative stress.
Conclusion
As a precursor to the vital NAD+ coenzyme, NMN supports various metabolic processes, DNA repair, and cellular energy production. The market offers numerous options, but discerning the best among them is essential for maximizing benefits.
Wonderfeel, with its robust, antioxidant-rich formula, provides a comprehensive approach to wellness. Renue By Science leverages advanced liposomal technology for superior absorption. Purovitalis and DoNotAge offer high-purity NMN with a commitment to quality and transparency. ProHealth Longevity provides versatile and pharmaceutical-grade options, while MoleQlar delivers exceptional purity and participates in significant clinical trials.
Each brand brings unique strengths, from innovative delivery methods to rigorous third-party testing, ensuring you receive top-tier supplements. As you navigate the NMN supplement landscape, consider your specific health goals, budget, and the factors outlined to make an informed choice.
Investing in high-quality NMN supplements can be a pivotal step towards enhancing your vitality, energy levels, and overall well-being. Embrace the journey to better health with confidence, knowing that the right NMN supplement can help you unlock the benefits of cellular rejuvenation and longevity.
Science behind NMN and its potential benefits
How NMN can help you reclaim your vitality and enjoy a healthier life
NMN BenefitsRelevant posts
Wonderfeel Youngr NMN Review | Aging Reimagined
Renue By Science Review | Liposomal NMN And Science-driven Wellness
